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UGID:715642     UniGene Hs.500483     Homo sapiens (human)   ACTA2
Actin, alpha 2, smooth muscle, aorta (ACTA2)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_031418.1 actin, alpha 2, smooth muscle, aorta M. musculus 100.0 376
NP_112266.1 smooth muscle alpha-actin R. norvegicus 100.0 376
XP_001370562.1 PREDICTED: similar to alpha-cardiac actin M. domestica 100.0 376
NP_997785.1 actin, alpha 2, smooth muscle, aorta D. rerio 100.0 376
NP_001084806.1 hypothetical protein LOC431847 X. laevis 100.0 376
NP_001011250.1 actin, alpha 2, smooth muscle, aorta X. tropicalis 100.0 376
NP_001026400.1 actin, alpha 2, smooth muscle, aorta G. gallus 100.0 376
XP_001506759.1 PREDICTED: similar to alpha-smooth muscle actin O. anatinus 100.0 376
XP_001088312.1 PREDICTED: similar to Actin, alpha cardiac (Alpha-cardiac actin) isoform 2 M. mulatta 100.0 376
XP_521550.2 PREDICTED: similar to alpha-smooth muscle actin isoform 7 P. troglodytes 100.0 376
NP_001604.1 alpha 2 actin H. sapiens 100.0 376
XP_534781.2 PREDICTED: similar to Actin, aortic smooth muscle (Alpha-actin 2) C. lupus familiaris 100.0 376
XP_001503085.1 PREDICTED: actin, alpha 2, smooth muscle, aorta E. caballus 100.0 376
XP_001924531.1 PREDICTED: actin, alpha, cardiac muscle 1 S. scrofa 100.0 376
NP_001029674.1 actin, aortic smooth muscle B. taurus 100.0 376
NP_001095152.1 alpha-smooth muscle actin O. cuniculus 100.0 376
NP_001117011.1 fast myotomal muscle actin S. salar 99.7 376
NP_505818.1 T04C12.5 C. elegans 97.6 375
NP_511052.1 Actin 5C CG4027-PB, isoform B D. melanogaster 97.3 375
XP_001699068.1 actin C. reinhardtii 94.4 376
NP_187818.1 ACT11 (ACTIN-11); structural constituent of cytoskeleton A. thaliana 93.4 376
NP_116614.1 Actin, structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions; Act1p S. cerevisiae 91.7 374
XP_961133.2 actin N. crassa 91.7 374

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: neonate [show more like this]
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented in several libraries
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: uterus; lung; prostate; intestine; vascular; stomach; pancreas; brain; placenta; connective tissue; uncharacterized tissue; eye; umbilical cord; kidney; mammary gland; testis; mixed; bone marrow; skin; bone; muscle; spleen; adipose tissue; heart; liver; ovary; embryonic tissue; trachea; pharynx; nerve; thyroid; pituitary gland; thymus; blood; cervix; ganglia; esophagus; adrenal gland; epididymis; amniotic fluid; spinal cord; bladder; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q23.3
UniSTS entry: Chr 10 D10S2177
UniSTS entry: Chr 10 RH44176
UniSTS entry: Chr 10 (n/a)
UniSTS entry: Chr 9 PMC23952P1
UniSTS entry: Chr 10 RH45184
UniSTS entry: Chr 10 GDB:193855
UniSTS entry: Chr 7 (n/a)
UniSTS entry: Chr 5 (n/a) [Map Viewer]
UniSTS entry: Chr Y D3S1674
UniSTS entry: Chr 7 PMC305873P2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

BX647362.1 Homo sapiens mRNA; cDNA DKFZp686P1462 (from clone DKFZp686P1462) A
AK127229.1 Homo sapiens cDNA FLJ45296 fis, clone BRHIP3003340 P
NM_001613.1 Homo sapiens actin, alpha 2, smooth muscle, aorta (ACTA2), mRNA P
J05192.1 Human alpha-actin (ACTA) mRNA, complete cds P
CR536518.1 Homo sapiens full open reading frame cDNA clone RZPDo834A1120D for gene ACTA2, actin, alpha 2, smooth muscle, aorta; complete cds, incl. stopcodon P
CR622200.1 full-length cDNA clone CS0DN001YJ05 of Adult brain of Homo sapiens (human) P
CR621459.1 full-length cDNA clone CS0DI076YA06 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR619420.1 full-length cDNA clone CS0DI028YH12 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR597033.1 full-length cDNA clone CS0DI083YP08 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR592949.1 full-length cDNA clone CS0DE007YB06 of Placenta of Homo sapiens (human) P
CR591183.1 full-length cDNA clone CS0DN005YH10 of Adult brain of Homo sapiens (human) P
CR590615.1 full-length cDNA clone CS0DE002YN18 of Placenta of Homo sapiens (human) P
BC093052.1 Homo sapiens actin, alpha 2, smooth muscle, aorta, mRNA (cDNA clone MGC:111131 IMAGE:30351093), complete cds PA
AK025094.1 Homo sapiens cDNA: FLJ21441 fis, clone COL04422 A
AY692464.1 Homo sapiens growth-inhibiting gene 46 mRNA, complete cds PA
BC017554.2 Homo sapiens actin, alpha 2, smooth muscle, aorta, mRNA (cDNA clone MGC:9221 IMAGE:3906861), complete cds PA
AK313294.1 Homo sapiens cDNA, FLJ93806, Homo sapiens actin, alpha 2, smooth muscle, aorta (ACTA2), mRNA P
X13839.1 Human mRNA for vascular smooth muscle alpha-actin P
AK300664.1 Homo sapiens cDNA FLJ52761 complete cds, highly similar to Actin, aortic smooth muscle PA

EST sequences (10 of 1584) [Show all sequences]

AA865183.1 Clone IMAGE:1459102 kidney 3' read A
AA864475.1 Clone IMAGE:1460102 kidney 3' read PA
AA968827.1 Clone IMAGE:1570043 lung 3' read PA
AA970229.1 Clone IMAGE:1575191 kidney 3' read PA
AA975356.1 Clone IMAGE:1588683 kidney 3' read A
AA902787.1 Clone IMAGE:1519505 uncharacterized tissue 3' read P
AI002978.1 Clone IMAGE:1699545 kidney 3' read P
AI003916.1 Clone IMAGE:1621835 testis 3' read P
AI014735.1 Clone IMAGE:1598750 uncharacterized tissue 3' read PA
AI027715.1 Clone IMAGE:1644541 testis 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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