Collagen, type I, alpha 1, Homo sapiens

Restricted Expression:

embryoid body [show more like this]

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]

Highly represented in many libraries

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

embryonic tissue; bone; eye; lung; skin; uncharacterized tissue; mammary gland; intestine; pancreas; bone marrow; placenta; connective tissue; ear; mixed; brain; ovary; stomach; thyroid; uterus; heart; mouth; amniotic fluid; bladder; larynx; kidney; epididymis; spleen; pituitary gland; prostate; esophagus; vascular; nerve; testis; muscle; liver; adrenal gland; umbilical cord; pharynx; blood; lymph node; salivary gland; ganglia; lymph; adipose tissue; thymus

NCBI

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Finding cDNAs

UGID:158287 UniGene Hs.172928 Homo sapiens (human) COL1A1

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Collagen, type I, alpha 1 (COL1A1)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
XP_863148.1	PREDICTED: similar to Collagen alpha 1(III) chain precursor isoform 12	C. lupus familiaris	68.7	1465
XP_912463.1	PREDICTED: similar to collagen, type XXII, alpha 1, isoform 3	M. musculus	49.5	1188
NP_647970.1	CG10625 CG10625-PA, isoform A	D. melanogaster	47.8	201
NP_001022663.1	K04H4.1b	C. elegans	46.6	1281

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	17
	Map position:	17q21.33

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_000088.3	Homo sapiens collagen, type I, alpha 1 (COL1A1), mRNA
K01228.1	Human proalpha 1 (I) chain of type I procollagen mRNA (partial)	P
AB209597.1	Homo sapiens mRNA for Collagen alpha 1 chain precursor variant protein	P
Z74615.1	H.sapiens mRNA for prepro-alpha1(I) collagen	P
BC036531.2	Homo sapiens collagen, type I, alpha 1, mRNA (cDNA clone MGC:33668 IMAGE:5264710), complete cds	PA
X06269.1	Human mRNA for pro-1(I)collagen chain (Col1A1)	P
X07884.1	Human mRNA for alpha-1(I) chain of procollagen type I	P
M36546.1	Human alpha-1 collagen type I mRNA, 5' end	P
S64596.1	COL1A1=type I collagen pro alpha 1(I) chain propeptide {3' region} [human, fetal cells 86-237, 86-146, 88-251, mRNA Partial Mutant, 855 nt]	P

EST sequences (10 of 3503) [Show all sequences]

AA961662.1	Clone IMAGE:1592694	kidney	3' read	PA
AA961963.1	Clone IMAGE:1593803	kidney	3' read	P
AA864333.1	Clone IMAGE:1470682	uncharacterized tissue	3' read	A
AA975668.1	Clone IMAGE:1591055	kidney	3' read
AA977821.1	Clone IMAGE:1592444	kidney	3' read	P
AA978078.1	Clone IMAGE:1590866	kidney	3' read	A
AA983262.1	Clone IMAGE:1592488	kidney	3' read	P
AA985449.1	Clone IMAGE:1594166	kidney	3' read	A
AA985499.1	Clone IMAGE:1592932	kidney	3' read
AA987731.1	Clone IMAGE:1593998	kidney	3' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria