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UGID:149994     UniGene Hs.133892     Homo sapiens (human)   TPM1 Order cDNA clone, Links
Tropomyosin 1 (alpha) (TPM1)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
XP_001103298.1 PREDICTED: similar to tropomyosin 1, alpha isoform b isoform 9 M. mulatta 100.0 325
XP_001173556.1 PREDICTED: hypothetical protein isoform 3 P. troglodytes 100.0 325
NP_077745.2 tropomyosin 1, alpha M. musculus 100.0 283
NP_001029241.1 tropomyosin 1, alpha isoform b R. norvegicus 100.0 283
XP_001366077.1 PREDICTED: similar to tropomyosin 2, fibroblast - rat isoform 6 M. domestica 100.0 283
NP_001018004.1 tropomyosin 1 alpha chain isoform 3 H. sapiens 100.0 283
NP_001013608.1 tropomyosin 1 alpha chain B. taurus 100.0 283
NP_001119823.1 tropomyosin 1 (alpha) O. aries 100.0 283
NP_001099158.1 alpha-tropomyosin O. cuniculus 100.0 283
NP_001090952.1 tropomyosin 1 (alpha) S. scrofa 99.7 283
NP_571180.1 alpha-tropomyosin D. rerio 96.1 283
NP_001128548.1 alpha-skeletal tropomyosin X. laevis 95.4 283
NP_001021695.1 LEVamisole resistant family member (lev-11) C. elegans 65.2 282
NP_732002.1 Tropomyosin 1 CG4898-PD, isoform D D. melanogaster 61.9 281

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented in several libraries
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: heart; embryonic tissue; muscle; brain; placenta; liver; intestine; uterus; eye; prostate; kidney; lung; stomach; vascular; uncharacterized tissue; pancreas; skin; mammary gland; mixed; bone; testis; umbilical cord; trachea; esophagus; spleen; amniotic fluid; bladder; ovary; thyroid; pharynx; blood; mouth; salivary gland; connective tissue; lymph node; ear; cervix; bone marrow; spinal cord; ascites; nerve; adrenal gland; ganglia; pituitary gland; epididymis; thymus; adipose tissue; larynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q22.1
UniSTS entry: Chr 15 A006I38
UniSTS entry: Chr 15 G20856
UniSTS entry: Chr 15 RH69090
UniSTS entry: Chr 15 SHGC-31495
UniSTS entry: Chr 15 SHGC-12376
UniSTS entry: Chr 15 G30945
UniSTS entry: Chr 15 RH92957
UniSTS entry: RH70111
UniSTS entry: D10S2366
UniSTS entry: RH44940
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (67)

BC050473.1 Homo sapiens tropomyosin 1 (alpha), mRNA (cDNA clone IMAGE:5732846), partial cds PA
AL050179.1 Homo sapiens mRNA; cDNA DKFZp586K2222 (from clone DKFZp586K2222) PA
BC053545.1 Homo sapiens tropomyosin 1 (alpha), mRNA (cDNA clone MGC:61803 IMAGE:5730451), complete cds PA
BX648171.1 Homo sapiens mRNA; cDNA DKFZp686K239 (from clone DKFZp686K239) A
AK129882.1 Homo sapiens cDNA FLJ26372 fis, clone HRT06233 P
NM_000366.5 Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 5, mRNA PA
AK131384.1 Homo sapiens cDNA FLJ16459 fis, clone BRCAN2002473, moderately similar to Tropomyosin, fibroblast isoform 2 P
AY640415.1 Homo sapiens tropomyosin alpha striated muscle isoform (TPM1) mRNA, complete cds; alternatively spliced P
AY640414.1 Homo sapiens sarcomeric tropomyosin kappa (TPM1) mRNA, complete cds; alternatively spliced P
CR626242.1 full-length cDNA clone CS0DI018YG03 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR625156.1 full-length cDNA clone CS0DA008YE05 of Neuroblastoma of Homo sapiens (human) P
CR623950.1 full-length cDNA clone CS0DE013YD14 of Placenta of Homo sapiens (human) P
CR623323.1 full-length cDNA clone CS0DN004YK09 of Adult brain of Homo sapiens (human) P
CR623222.1 full-length cDNA clone CL0BB009ZA04 of Neuroblastoma of Homo sapiens (human) P
CR622076.1 full-length cDNA clone CS0DE009YD04 of Placenta of Homo sapiens (human) P
CR621772.1 full-length cDNA clone CS0DE003YF10 of Placenta of Homo sapiens (human) P
CR620556.1 full-length cDNA clone CS0DI017YL03 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR619070.1 full-length cDNA clone CS0DI070YE04 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR618272.1 full-length cDNA clone CS0DI066YN15 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR612660.1 full-length cDNA clone CS0DI072YE02 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR610855.1 full-length cDNA clone CS0DC007YK17 of Neuroblastoma Cot 25-normalized of Homo sapiens (human) P
CR610269.1 full-length cDNA clone CS0DJ015YG14 of T cells (Jurkat cell line) Cot 10-normalized of Homo sapiens (human) P
CR607922.1 full-length cDNA clone CS0DE001YI05 of Placenta of Homo sapiens (human) P
CR607666.1 full-length cDNA clone CS0DI079YM21 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR607138.1 full-length cDNA clone CS0DI003YP09 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR605281.1 full-length cDNA clone CS0DE010YN20 of Placenta of Homo sapiens (human) P
CR604708.1 full-length cDNA clone CS0DI042YJ04 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR604315.1 full-length cDNA clone CS0DM008YD22 of Fetal liver of Homo sapiens (human) P
CR603403.1 full-length cDNA clone CS0DI004YK17 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR603337.1 full-length cDNA clone CS0DF027YA22 of Fetal brain of Homo sapiens (human) P
CR602634.1 full-length cDNA clone CS0DC017YK08 of Neuroblastoma Cot 25-normalized of Homo sapiens (human) P
CR602172.1 full-length cDNA clone CS0DE008YF05 of Placenta of Homo sapiens (human) P
CR601382.1 full-length cDNA clone CS0DI081YG06 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR598963.1 full-length cDNA clone CS0DM006YH21 of Fetal liver of Homo sapiens (human) P
CR597428.1 full-length cDNA clone CS0DI012YG18 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR595152.1 full-length cDNA clone CL0BA009ZA04 of Placenta of Homo sapiens (human) P
CR594134.1 full-length cDNA clone CS0DI079YO17 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR593513.1 full-length cDNA clone CS0DI065YB19 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR593146.1 full-length cDNA clone CS0DB001YO19 of Neuroblastoma Cot 10-normalized of Homo sapiens (human) P
CR591288.1 full-length cDNA clone CS0DI086YE21 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR590047.1 full-length cDNA clone CS0DJ006YP17 of T cells (Jurkat cell line) Cot 10-normalized of Homo sapiens (human) P
AB209041.1 Homo sapiens mRNA for TPM1 protein variant protein P
NM_001018020.1 Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 7, mRNA PA
NM_001018008.1 Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 6, mRNA P
NM_001018007.1 Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 2, mRNA PA
NM_001018006.1 Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 4, mRNA PA
NM_001018005.1 Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 1, mRNA PA
NM_001018004.1 Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 3, mRNA PA
DQ424903.1 Homo sapiens clone FG060306 tropomyosin 1 alpha variant 6 mRNA, complete cds, alternatively spliced P
M19713.1 Human skeletal muscle alpha-tropomyosin (hTM-alpha) mRNA, complete cds PA
M19714.1 Human skeletal muscle alpha-tropomyosin gene (hTM-alpha) mRNA, 3' end P
M19715.1 Human skeletal muscle alpha-tropomyosin (hTM-alpha) mRNA, 3' end P
BC007433.2 Homo sapiens tropomyosin 1 (alpha), mRNA (cDNA clone MGC:4021 IMAGE:2962925), complete cds PA
AK057989.1 Homo sapiens cDNA FLJ25260 fis, clone STM04650, highly similar to TROPOMYOSIN, FIBROBLAST ISOFORM 2 P
AK055197.1 Homo sapiens cDNA FLJ30635 fis, clone CTONG2002520
AK309170.1 Homo sapiens cDNA, FLJ99211 P
AK094175.1 Homo sapiens cDNA FLJ36856 fis, clone ASTRO2014863
AK092573.1 Homo sapiens cDNA FLJ35254 fis, clone PROST2003775, highly similar to TROPOMYOSIN, FIBROBLAST ISOFORM TM3 P
BC015871.1 Homo sapiens, clone IMAGE:4703227, mRNA A
AF474156.1 Homo sapiens TPMsk1 (TPM1) mRNA, partial cds P
AL358752.1 Homo sapiens EST from clone 545144, 5' end
L02923.1 Human tropomyosin isoform hTMsma mRNA, exon 2
L02922.1 Human tropomyosin isoform hTM5a mRNA, exon 1
Z24727.1 H.sapiens tropomyosin isoform mRNA, complete CDS P
X12369.1 Human mRNA (exon 6-9 part.) for smooth muscle tropomyosin P
AJ000147.1 Homo sapiens mRNA for alpha-tropomyosin (3' end) A
AJ001055.1 Homo sapiens mRNA for alpha-tropomyosin A

EST sequences (10 of 2146) [Show all sequences]

R15972.1 Clone IMAGE:53242 brain 3' read A
R15973.1 Clone IMAGE:53242 brain 5' read
AA976487.1 Clone IMAGE:1591802 kidney 3' read A
AA985408.1 Clone IMAGE:1592825 kidney 3' read A
AA992675.1 Clone IMAGE:1623203 embryonic tissue 3' read A
AA994539.1 Clone IMAGE:1631958 mammary gland 3' read
R16635.1 Clone IMAGE:129658 mixed 5' read
AA996250.1 Clone IMAGE:1605697 kidney 3' read A
AA999872.1 Clone IMAGE:1636401 kidney 3' read A
AA838437.1 Clone IMAGE:1422552 kidney


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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