Dr. Paul S. Albert

Office Address:
Room 8136
6130 Executive Plaza
Rockville, MD 20852

Contact Information:
Tel: (301) 496-4051
Fax: (301) 402-0560
Email:Albertp@ctep.nci.nih.gov

Research Interests
Longitudinal data analysis, diagnostic and measurement error, missing data, the analysis of biomarker data.

Selected Publications 
As of Jan 5, 2009

Albert, P.S., McFarland, H.F., Smith, M.E., and Frank, J.A. Time series for counts from a relapsing-remitting disease: application to modeling the disease course in multiple sclerosis. Statistics in Medicine 13: 453-466, 1994.

Albert, P.S. A Markov model for sequences of ordinal data from a relapsing-remitting disease. Biometrics 50, 51-60, 1994.

Albert, P.S. and McShane, L.M. A generalized estimating equations approach for spatially correlated binary data: with an application to the analysis of neuroimaging data. Biometrics 51: 627-638, 1995.

McShane, L.M., Albert, P.S., and Palmatier, M. A latent processes regression for spatially correlated counts. Biometrics 53: 1116-1124, 1997.

Albert, P.S., Follmann, D.A., and Barnhart, H.X. A generalized estimating equation approach for modeling random-length binary vector data. Biometrics 53: 1116-1124, 1997.

Albert, P.S., Hunsberger, S.A., and Biro, F. Modeling repeated measures with monotonic ordinal response and misclassification error, with applications to studying maturation. Journal of the American Statistical Association 92: 1304-1312, 1997.

Albert, P.S. and Waclawiw, M.A. A two state Markov chain for heterogeneous transitional data: a quasi-likelihood approach. Statistics in Medicine 17: 1481-1493, 1998.

Follmann, D.A. and Albert, P.S. Bayesian monitoring of event rates with censored data. Biometrics 55, 603-607, 1999.

Albert, P.S. A mover-stayer model for longitudinal marker data. Biometrics 55, 1252-1257, 1999.

Shih, J.H. and Albert P.S. A latent model for correlated binary data with diagnostic error. Biometrics 55, 1232-1235, 1999.

Follmann, D.A., Hunsberger, S.A., and Albert, P.S. Repeated probit regression when covariates are measured with error. Biometrics 55, 603-607, 1999.

Albert, P.S. Tutorial in Biostatistcs: Longitudinal data analysis (repeated measures) in clinical trials.  Statistics in Medicine18, 1707-1732, 1999.

Albert, P.S.  A transitional model for longitudinal binary data subject to nonignorable missing data. Biometrics 56, 602-608, 2000.

Albert, P.S. and Follmann, D.A. Modeling longitudinal count data subject to informative dropout. Biometrics 56, 667-677,2000

Wu, M.C., Albert, P.S., and Wu, B.U. Adjusting for dropout in clinical trials with repeated measures: design and analysis issues. Statistics in Medicine 20, 93-108, 2001.

Albert, P.S., McShane, L.M., Shih, J.H. and the U.S. National Cancer Institute (NCI) Bladder Tumor Marker Network. Latent class modeling approaches for assessing diagnostic error without a gold standard: with applications to p53 immunohistochemical assays in bladder tumors. Biometrics 57, 610-619,2001.

Albert, P.S., Ratnasinghe, D., Tangrea, J., and Wacholder, S.  Limitations of the case-only design for identifying gene-environment interactions. The American Journal of Epidemiology 154, 687-693,2001.

Hunsberger, S., Albert, P.S., Follmann, D.A., and Suh, E. Parametric and semiparametric approaches to testing for seasonal trend in serial count data.  Biostatistics 3, 289-298, 2002.

Albert, P.S., Follmann, D.A., Wang, S.A., and Suh, E.B. A latent autoregressive model for longitudinal binary data subject to nonignorable missingness. Biometrics 58, 631-642, 2002.

Albert, P.S., McShane, L.M., and Korn, E.L. The design of a binary biomarker study from the results of a pilot reproducibility study.  Biometrics 58, 576-585, 2002.

Wu, M., Borkowf, C, and Albert, P.S.  The analysis of longitudinal quality of life data with informative dropout. Statistical Design, Measurement and Analysis of Health Related Quality of Life. Edited by Mounir Mesbah, Bernard Cole, and Mei-ling Ting Lee. Kluwer Academic Publishers, 2002.

Albert, P.S. and Borkowf, C. An introduction to biostatistics: randomization, hypothesis testing, and sample size.  Principles and Practice of Clinical Research. Edited by John Gallin. Academic Research, 2002.

Albert, P.S. and Follmann, D.A. A random effects transition model for binary longitudinal data with informative missingness. Invited paper in a special volume: Incomplete Data: imputation and model based approaches.  Statistica Neerlandica 57, 100-111, 2003.

Borkowf, C.B., Albert, P.S., and Abnet, C.C. Using lowess to remove systematic trends in predictor variables before logistic regression with quantile-categories. Statistics in Medicine 22,1477-1494, 2003.

Albert, P.S and Shih, J.H. Modeling tumor growth with random onset. Biometrics 59, 897-906, 2003.

Albert, P.S. and Wu, M.C. Longitudinal data analysis with missingness. Contemporary Issues in Clinical Trials. Editor: Nancy Geller. Marcel Decker, 2004.

Albert, P.S. and Dodd, L. A cautionary note on the robustness of latent class models for estimating diagnostic error without a gold standard. Biometrics 60, 427-435, 2004.

Albert, P.S., Hunsberger, S.A., Hu, N., and Taylor, P. Identifying multiple change points in heterogeneous binary data with an application to molecular genetics. Biostatistics 5, 515-529, 2004.

Albert, P.S. Longitudinal data analysis (repeated measures) in clinical trials. Tutorials in Biostatistics: Volume I. Editor: R.B. D'Agostino. Wiley Press, 2004.

Albert, P.S. Missclassification Models. Encylopedia of Biostatistics, 2nd Edition. Editors: Peter Armitage and Theodore Colton, Wiley Press, 2005.

Korn, E.L., Albert, P.S., and McShane, L.M. Assessing surrogates as trial endpoints using mixed models. Statistics in Medicine 24, 163-182.

Albert, P.S. and Shen J. Modeling longitudinal semi-continuous emesis volume data with serial correlation in an acupuncture clinical trial.
Journal of the Royal Statistical  Society: Series C: Applied Statistics 54, 707-720, 2005.

Albert, P.S. On the interpretation of marginal inference with a mixture model for clustered semi-continuous data. Biometrics 61,  879-880, 2005.

Albert, P.S. and Hunsberger, S. On analyzing circadian rhythm data using non-linear mixed models with harmonic terms. Biometrics  61, 1115-120, 2005.

Borkowf, C.B. and Albert, P.S. Efficient estimation of risk of a disease by quantile-categories of a predictor variable using generalized additive models. Statistics in Medicine 24, 623-645, 2005.

Albert, P.S. and Follmann, D.A. Random effects and latent process approaches for longitudinal binary data with missingness: With an application to the analysis of opiate clinical trial data. Statistical Methods in Medical Research 18, 417-439, 2007.

Johnson, L.L.,  Borkowf, C, Albert, P.S.. An introduction to biostatistics: randomization, hypothesis testing, and sample size.  Principles and Practice of Clinical Research, 2nd Edition . Edited by John Gallin. Academic Research, 2007

Albert, P.S. Imputation approaches for estimating diagnostic accuracy for multiple tests from partial verified designs. Biometrics 63, 947-957, 2007.

Albert, P.S. Random effects modeling approaches for estimating ROC curves from repeated ordinal tests without a gold standard. Biometrics 63, 593-602, 2007.

Albert, P.S. and Dodd, L.E. On estimating diagnostic accuracy from studies with multiple raters and partial gold standard evaluation. Journal of the American Statistical Association 103, 61-73, 2008.

Albert, P.S. Modeling longitudinal biomarker data with multiple assays which have known detection limits. Biometrics 64, 527-537, 2008.

Albert, P.S. Estimating diagnostic accuracy of multiple binary tests with an imperfect reference standard. Statistics in Medicine Online Early DOI: 10.1002/sim.3514, 2008.

Albert, P.S. and Follmann, D.A. Shared random parameter models. In Longitudinal Data Analysis: A Handbook of Modern Statistical Methods. Edited by Garret Fitzmaurice, Marie Davidian, Geert Verbeke, and Geert Molenberghs. Chapman and Hall Press, 433-452, 2008.

Ghosh, P. and Albert, P.S. A Bayesian analysis for longitudinal semi-continuous data with an application to an acupuncture clinical trial. Computational Statistics and Data Analysis 53, 699-706, 2009.

Hunsberger, S., Albert, P.S., and London, W.B. A finite mixture survival model to characterize risk groups of neuroblastoma. In Press at Statistics in Medicine.

Albert, P.S. The analysis of categorical data in medical studies. In Medical Uses of Statistics, 3rd Edition. Editors: Bailar and Hoaglin, New England Journal of Medicine Press.

Please send comments and suggestions to brb@linus.nci.nih.gov

Last updated: Jan 5, 2009