Selected Recent Publications
Rubinstein, L.V., Shoemaker, R.H., Paull, K.D., Simon,
R.M., Tosini, S., Skehan, P., Scudiero, D.A., Monks, A., and Boyd,
M.R.: Comparison
of in vitro anticancer drug screening data generated with a tetrazolium
assay versus a protein assay against a diverse panel of human tumor
cell lines. J. Nat. Cancer Inst. 82:1113-1118, 1990.
Grem, J.L., Rubinstein, L., King, S.A., Cheson, B.D.,
Hawkins, M.J., and Shoemaker, D.D: Clinical toxicity associated with
tiazofurin. Investig. New Drugs 8:227-238, 1990.
Hricak, J., Rubinstein, L.V., Gherman, G. and Karstaedt,
N.: MR imaging evaluation of endometrial carcinoma: results of an
NCI cooperative study, Radiology 179:829-832, 1991.
Boyd, N.R., Paull, K.D., and Rubinstein, L.V.: "Data
display and analysis strategies for the new NCI disease-oriented in-vitro
anti-tumor drug screen." in Valeriote, F.A., Corbett, T.H.,
and Baker, L.H.(eds.), Cytotoxic Anticancer Drugs: Models and Concepts
for Drug Discovery and Development, Kluwer Academic Publ., Norwell,
Mass., 11-34, 1992.
Walton, L.A., Yadusky, A., Rubinstein, L., Roth, L.M.,
and Young, R.C.: Stage II carcinoma of the ovary: an analysis of survival
after comprehensive surgical staging and adjunctive therapy. Gynecol.
Oncol. 44:55-60, 1992.
Hodes, L., Paull, K., Koutsoukos, A., Rubinstein,
L.: Measures
of selectivity and similarity for drug responses in a panel of human
tumor cell lines. J. Biopharm. Statist. 2:31-48,
1992.
Weinstein, J.N., Kohn, K.W., Grever, M.R., Viswanadhan,
V.N., Rubinstein, L.V., Monks, A., Scudiero, D.A., Welch L., Koutsoukos,
A., Paull, K.D.: Neural
computing in cancer drug development: Predicting mechanism of action,
Science 258:447-451, 1992.
The Lung Cancer Study Group, prepared by R. Feld,
L. Rubinstein, P. Thomas: Adjuvant chemotherapy after surgery for
T1N1 and T2N0 non-small
cell lung cancer, J. Nat. Cancer Inst. 85:299-306, 1993.
Weinstein, J.N., Rubinstein, L.V., Koutsoukos, A.D.,
Kohn, K.W., Grever, M.R., Monks, A., Scudiero, D.A., Welch, L., Chiausa,
A.J., Fojo, A.T., Viswanadhan, V.N., Paull, K.D., Neural networks
in the discovery of new treatments for cancer and AIDS, World Congress
on Neural Networks 1:111-116, 1993.
The Lung Cancer Study Group, prepared by Thomas, P.A.
and Rubinstein, L.: Malignant disease appearing late after operation
for T1N0 non-small cell lung cancer, J. Thorac.
Surg. 106:1053-1058, 1993.
Koutsoukos, A.D. Rubinstein, L.V., Faraggi, D., Simon,
R.M., Kalyandrug, S., Weinstein, J.N., Paull, K.D., Kohn, K.W., Discrimination
techniques applied to the NCI in vitro antitumor drug screen: predicting
biochemical mechanism of action, Stat. in Med. 13:719-730,
1994.
Korn, E.L., Midthune, D., Chen, T.T., Rubinstein,
L.V., Simon, R.M.: A
comparison of two phase I trial designs, Stat. in Med.
13:1799-1806, 1994.
The Lung Cancer Study Group, prepared by R. Ginsberg
and L. Rubinstein: Lobectomy versus limited resection in stage I NSCLC,
Annals of Thoracic Surgery 60:615-623, 1995.
Trimble, E.L., Rubinstein, L., Menck, H., Hankey,
B., Kosary, C., Giusti, R., Vaginal clear cell adenocarcinoma in the
United States, Gynecologic Oncology 61:113-115, 1996.
Koo, H.-M., Monks, A., Mikheev, A., Rubinstein, L.V.,
Gray-Goodrich, M., McWilliams, M.J., Alvord, W.G., Oie, H.K., Gazdar,
A.F., Paull, K.D., Zarbl, H., Vande Woude, G.F.: Enhanced sensitivity
to cytosine arabinoside and topoisomerase II inhibitors in tumor cell
lines harboring activated Ras oncogenes, Cancer Research 56:5211-5216,
1996.
Weinstein, J.N., Myers, T,, O’Connor, P.M., Friend,
S.H., Fornace, A.J., Kohn, K.W., Fojo, A., Bates, S.E., Rubinstein,
L.V., Anderson, N.L., Buolamwini, J.K., van Osdol, W.W., Monks, A.P.,
Scudiero, D.A., Sausville, E.A., Zaharevitz, D.G., Bunow, B., Viswanadhan,
V.N., Johnson, G.S., Wittes, R.E., Paull, K.: An
information-intensive approach to the molecular pharmacology of cancer.
Science 275:343-349, 1997.
Smith, M.A., Ungerleider, R., Korn, E.L., Rubinstein,
L.V., Simon, R.M.: The role of independent data monitoring committees
in randomized clinical trials sponsored by the National Cancer Institute,
J. of Clinical Oncology, 15:2736-2743, 1997.
Simon, R.M., Freidlin, B., Rubinstein, L.V., Arbuck,
S., Collins, J., Christian, M.: Accelerated
titration designs for phase I clinical trials in oncology, J.
Nat. Cancer Inst., 89:1138-1147, 1997.
Rubinstein, L.V., Ungerleider, R., Cooperative cancer
trials, in Armitage, P. and Colton, T. (eds.), Encylopedia
of Biostatistics, John Wiley & Sons, Chichester, 933-941,
1998.
Rubinstein, L.V., Statistical review for medical journals,
guidelines for authors, in Armitage, P. and Colton, T. (eds.),
Encylopedia of Biostatistics, John Wiley & Sons, Chichester,
4275-4278, 1998.
Smith, M.A., Rubinstein, L., Anderson, J., Catalano,
P.J., Freidlin, B., Heyn, R., Khayat, A., Krailo, M., Land, V., Miser,
J., Shuster, J., Vena, D., Second report of the Cancer Therapy Evaluation
Program (CTEP) monitoring plan for secondary leukemia or myelodysplastic
syndrome following treatment with epipodophyllotoxins, Journal
of Clinical Oncology, 17(2): 569-77, 1999.
Therasse, P., Arbuck, S.G., Eisenhauer, E.A., Wanders,
J., Kaplan, R.S., Rubinstein, L. Verweij, J., van Glabbeke, M., van
Oosterom, A., Christian, M.C., Gwyther, S.G., New Guidelines to Evaluate
the Response to Treatment in Solid Tumors, J. Nat. Cancer Inst.,
92:205-16, 2000.
Rubinstein, L.V., Therapeutic studies, in Allegra,
C.J. and Kramer, B.S. (eds.), Understanding Clinical Trials, Hematology/Oncology
Clinics of North America, W.B. Saunders Co., 14(4):849-876,
2000.
brb@linus.nci.nih.gov