Splicing factor, arginine/serine-rich 6, Homo sapiens

Expression Profile:

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Highly represented (2.1 pct) in cDNA library dbEST:5153, HT0408.

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

brain; blood; embryonic tissue; intestine; uterus; uncharacterized tissue; mixed; placenta; bone marrow; kidney; esophagus; vascular; mouth; spleen; thymus; nerve; trachea; adipose tissue; skin; thyroid; cervix; heart; eye; prostate; testis; mammary gland; pharynx; liver; lung; lymph node; bladder; ovary; larynx; adrenal gland; ear; stomach; ascites; connective tissue; muscle; pancreas; pituitary gland; bone; epididymis; parathyroid; amniotic fluid; salivary gland

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Finding cDNAs

UGID:131984 UniGene Hs.6891 Homo sapiens (human) SFRS6

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Splicing factor, arginine/serine-rich 6 (SFRS6)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
NP_006266.2	arginine/serine-rich splicing factor 6	H. sapiens	100.0	343
NP_080775.2	arginine/serine-rich splicing factor 6	M. musculus	99.1	338
NP_001008732.1	splicing factor, arginine/serine-rich 6	D. rerio	87.0	354
NP_788665.1	B52 CG10851-PA, isoform A	D. melanogaster	69.6	336
NP_001079543.1	similar to splicing factor, arginine/serine-rich 5 (SRp40, HRS)	X. laevis	66.7	257
NP_496442.1	SR Protein (splicing factor) family member (rsp-1)	C. elegans	58.4	310
XP_001690007.1	SR protein factor	C. reinhardtii	45.8	333
NP_850933.1	SR1 (splicing factor 2); RNA binding	A. thaliana	45.7	299

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	20
Map position:	20q12-q13.1
UniSTS entry:	Chr 20	RH47503
UniSTS entry:	Chr 20	NIB331
UniSTS entry:	Chr 20	RH18029
UniSTS entry:	Chr 20	SGC32867
UniSTS entry:	Chr 20	(n/a)

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

AL110214.1	Homo sapiens mRNA; cDNA DKFZp564J223 (from clone DKFZp564J223)	A
CR606848.1	full-length cDNA clone CS0DE008YO05 of Placenta of Homo sapiens (human)	P
CR605163.1	full-length cDNA clone CS0DH004YN13 of T cells (Jurkat cell line) of Homo sapiens (human)	P
CR591046.1	full-length cDNA clone CS0DL006YF19 of B cells (Ramos cell line) Cot 25-normalized of Homo sapiens (human)	P
AB208976.1	Homo sapiens mRNA for arginine/serine-rich splicing factor 6 variant protein	PA
U30828.1	Human splicing factor SRp55-2 (SRp55) mRNA, complete cds	P
U30883.1	Human splicing factor SRp55-1 (SRp-55) mRNA, complete cds	P
NM_006275.4	Homo sapiens splicing factor, arginine/serine-rich 6 (SFRS6), mRNA	PA
BC006832.2	Homo sapiens splicing factor, arginine/serine-rich 6, mRNA (cDNA clone MGC:5045 IMAGE:3449841), complete cds	PA
AK291203.1	Homo sapiens cDNA FLJ76823 complete cds, highly similar to Homo sapiens splicing factor, arginine/serine-rich 6 (SFRS6), mRNA	P
AB451375.1	Homo sapiens SFRS6 mRNA for splicing factor arginine/serine-rich 6, partial cds, clone: FLJ08061AAAF	P
AB451251.1	Homo sapiens SFRS6 mRNA for splicing factor arginine/serine-rich 6, complete cds, clone: FLJ08061AAAN	P

EST sequences (10 of 601) [Show all sequences]

R17184.1	Clone IMAGE:31922	brain	5' read
AI015227.1	Clone IMAGE:1624086	embryonic tissue	3' read	A
AI079810.1	Clone IMAGE:1659722	embryonic tissue	3' read	A
AA906661.1	Clone IMAGE:1522265	lung	3' read	A
AI122983.1	Clone IMAGE:1509543	mixed	3' read	A
AI122997.1	Clone IMAGE:1509879	mixed	3' read	A
AI127914.1	Clone IMAGE:1712692	uterus	3' read	A
AI141928.1	Clone IMAGE:1693460	heart	3' read	A
AI143562.1	Clone IMAGE:1708515	heart	3' read	A
CB045177.1	Clone IMAGE:3218169	intestine	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria