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UGID:222363     UniGene Hs.413812     Homo sapiens (human)   RAC1
Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) (RAC1)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_001004840.1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) X. tropicalis 100.0 191
XP_001506443.1 PREDICTED: similar to Chain B, Activated Rac1 Bound To Its Effector Phospholipase C Beta 2 O. anatinus 100.0 191
NP_008839.2 ras-related C3 botulinum toxin substrate 1 isoform Rac1 H. sapiens 100.0 191
NP_001003274.1 ras-related C3 botulinum toxin substrate 1 C. lupus familiaris 100.0 191
NP_566024.1 ARAC9/AtROP8/ROP8 (rho-related protein from plants 8); GTP binding A. thaliana 72.2 208
NP_477098.1 Rho1 CG8416-PA, isoform A D. melanogaster 69.5 189
XP_910736.1 PREDICTED: similar to Rho family GTPase RhoA M. musculus 67.0 187
XP_965740.1 protein RHO3 N. crassa 50.5 205

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented in several libraries
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: brain; pancreas; intestine; lung; uterus; mammary gland; skin; placenta; mixed; prostate; embryonic tissue; kidney; eye; liver; stomach; ascites; lymph; testis; mouth; uncharacterized tissue; bone; ovary; lymph node; muscle; thymus; spleen; heart; epididymis; adrenal gland; spinal cord; ear; pharynx; bladder; blood; cervix; connective tissue; thyroid; esophagus; pituitary gland; parathyroid; larynx; bone marrow; salivary gland; vascular; trachea; nerve; umbilical cord; ganglia; adipose tissue; tonsil
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 7
Map position: 7p22
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (25)

AJ132694.1 Homo sapiens mRNA for small GTPase rac1b P
M29870.1 Human ras-related C3 botulinum toxin substrate (rac) mRNA, complete cds P
M31467.1 Human ras-like protein mRNA, complete cds, clone TC25 P
BT007121.1 Homo sapiens ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) mRNA, complete cds P
BC050687.1 Homo sapiens ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1), mRNA (cDNA clone MGC:60264 IMAGE:6149377), complete cds PA
NM_006908.4 Homo sapiens ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) (RAC1), transcript variant Rac1, mRNA A
NM_198829.1 Homo sapiens ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) (RAC1), transcript variant Rac1c, mRNA PA
CR624866.1 full-length cDNA clone CS0DJ007YA22 of T cells (Jurkat cell line) Cot 10-normalized of Homo sapiens (human)
CR624356.1 full-length cDNA clone CS0CAP007YD23 of Thymus of Homo sapiens (human) P
CR621312.1 full-length cDNA clone CS0DI060YA06 of Placenta Cot 25-normalized of Homo sapiens (human) PA
CR612844.1 full-length cDNA clone CS0DL005YI17 of B cells (Ramos cell line) Cot 25-normalized of Homo sapiens (human) P
CR591797.1 full-length cDNA clone CS0DG004YC18 of B cells (Ramos cell line) of Homo sapiens (human) P
AY279384.1 Homo sapiens migration-inducing protein 5 (MIG5) mRNA, complete cds PA
NM_018890.3 Homo sapiens ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) (RAC1), transcript variant Rac1b, mRNA A
AF136373.1 Homo sapiens ras-related C3 botulinum toxin substrate isoform mRNA, complete cds P
AB209410.1 Homo sapiens mRNA for ras-related C3 botulinum toxin substrate 1 isoform Rac1b variant protein P
BC107748.1 Homo sapiens ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1), mRNA (cDNA clone MGC:111543 IMAGE:6699945), complete cds PA
BC004247.1 Homo sapiens ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1), mRNA (cDNA clone MGC:10547 IMAGE:3610745), complete cds PA
AK054993.1 Homo sapiens cDNA FLJ30431 fis, clone BRACE2008968, highly similar to Ras-related C3 botulinum toxin substrate 1 precursor P
AK291815.1 Homo sapiens cDNA FLJ77333 complete cds, highly similar to Homo sapiens ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) (RAC1), transcript variant Rac1b, mRNA
AK291806.1 Homo sapiens cDNA FLJ75553 complete cds, highly similar to Homo sapiens ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) (RAC1), transcript variant Rac1, mRNA
AF498964.1 Homo sapiens small GTP binding protein RAC1 (RAC1) mRNA, complete cds P
AJ012502.1 Homo sapiens mRNA activated in tumor suppression, clone TSAP22 A
U85236.1 Human IgM rheumatoid factor RF-MR27, variable heavy chain, mRNA, partial cds
D25274.1 Homo sapiens mRNA, clone:PO2ST9

EST sequences (10 of 1637) [Show all sequences]

AA954617.1 Clone IMAGE:1572776 kidney 3' read P
R14242.1 Clone IMAGE:28325 brain 5' read
AA922695.1 Clone IMAGE:1474336 intestine 3' read
R15768.1 Clone IMAGE:53261 brain 3' read A
R16272.1 Clone IMAGE:53261 brain 5' read
AA970772.1 Clone IMAGE:1576485 intestine 3' read
AA977398.1 Clone IMAGE:1589061 kidney 3' read P
AA991297.1 Clone IMAGE:1608874 mammary gland 3' read P
AA887564.1 Clone IMAGE:1500934 kidney 3' read P
AA910845.1 Clone IMAGE:1520722 kidney 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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