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UGID:1292999     UniGene Hs.533624     Homo sapiens (human)   H3F3A
Similar to histone (H3F3A)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
XP_001716494.1 PREDICTED: similar to histone H. sapiens 100.0 180
XP_001474439.1 PREDICTED: hypothetical protein M. musculus 100.0 135
NP_446437.1 H3 histone, family 3B R. norvegicus 100.0 135
XP_001368225.1 PREDICTED: hypothetical protein M. domestica 100.0 135
XP_001623766.1 predicted protein N. vectensis 100.0 135
NP_509344.1 HIStone family member (his-71) C. elegans 100.0 135
XP_001949594.1 PREDICTED: similar to Histone H3.3B CG8989-PA A. pisum 100.0 135
XP_975889.1 PREDICTED: similar to Histone H3.3B CG8989-PA isoform 2 T. castaneum 100.0 135
NP_001091756.1 h3 histone family 3a B. mori 100.0 135
XP_001657554.1 histone H3.3 A. aegypti 100.0 135
XP_321242.1 AGAP001813-PA A. gambiae 100.0 135
XP_001867328.1 histone H3.3 type 2 C. quinquefasciatus 100.0 135
NP_511095.1 Histone H3.3B CG8989-PA, isoform A D. melanogaster 100.0 135
XP_001120696.1 PREDICTED: similar to H3 histone, family 3B A. mellifera 100.0 135
XP_001178736.1 PREDICTED: similar to H3.3 histone S. purpuratus 100.0 135
XP_002119783.1 PREDICTED: similar to Histone H3.3B CG8989-PA C. intestinalis 100.0 135
NP_956297.1 H3 histone, family 3C D. rerio 100.0 135
NP_001080065.1 H3 histone, family 3B (H3.3B) X. laevis 100.0 135
NP_989026.1 H3 histone, family 3B (H3.3B) X. tropicalis 100.0 135
NP_990627.1 H3 histone, family 3B (H3.3B) G. gallus 100.0 135
XP_001514538.1 PREDICTED: hypothetical protein O. anatinus 100.0 135
XP_001091581.1 PREDICTED: similar to H3 histone, family 3B isoform 1 M. mulatta 100.0 135
XP_001140055.1 PREDICTED: hypothetical protein isoform 5 P. troglodytes 100.0 135
XP_537232.1 PREDICTED: similar to H3 histone, family 3B isoform 1 C. lupus familiaris 100.0 135
XP_001495110.1 PREDICTED: similar to Histone H3.3B CG8989-PA isoform 1 E. caballus 100.0 135
NP_999095.1 histone H3.3A S. scrofa 100.0 135
NP_001014411.1 H3 histone, family 3A B. taurus 100.0 135
NP_001078517.1 histone H3.2 A. thaliana 97.1 135
XP_328074.1 HISTONE H3 N. crassa 96.3 135
NP_009564.1 One of two identical histone H3 proteins (see also HHT2); core histone required for chromatin assembly, involved in heterochromatin-mediated telomeric and HM silencing; regulated by acetylation, methylation, and mitotic phosphorylation; Hht1p S. cerevisiae 95.6 135
XP_001690671.1 histone H3 C. reinhardtii 95.6 134

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented in several libraries
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: brain; uterus; stomach; pancreas; embryonic tissue; liver; lung; mixed; intestine; eye; testis; uncharacterized tissue; blood; placenta; prostate; muscle; ascites; larynx; epididymis; mammary gland; ovary; skin; tonsil; bone marrow; bone; spinal cord; kidney; lymph node; heart; thyroid; pituitary gland; thymus; vascular; mouth; cervix; lymph; umbilical cord; bladder; pharynx; pineal gland; esophagus; ear; spleen; parathyroid; nerve; adrenal gland; adipose tissue; salivary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 1q41
UniSTS entry: Chr X WI-6046
UniSTS entry: Chr 4 D15S1185
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

CR620119.1 full-length cDNA clone CS0DI012YE18 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR618614.1 full-length cDNA clone CS0DL002YP15 of B cells (Ramos cell line) Cot 25-normalized of Homo sapiens (human) P
CR613651.1 full-length cDNA clone CS0DJ011YI23 of T cells (Jurkat cell line) Cot 10-normalized of Homo sapiens (human) P
CR611775.1 full-length cDNA clone CS0DI039YF23 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR604105.1 full-length cDNA clone CS0DC005YN21 of Neuroblastoma Cot 25-normalized of Homo sapiens (human) P
CR595231.1 full-length cDNA clone CS0DM009YD06 of Fetal liver of Homo sapiens (human) P
CR594691.1 full-length cDNA clone CS0DB001YJ10 of Neuroblastoma Cot 10-normalized of Homo sapiens (human) P
M11354.1 Human H3.3 histone, class B mRNA, complete cds P
AK291102.1 Homo sapiens cDNA FLJ78487 complete cds, highly similar to Homo sapiens H3 histone, family 3A (H3F3A), mRNA P
AK311905.1 Homo sapiens cDNA, FLJ92171, Homo sapiens H3 histone, family 3A (H3F3A), mRNA P

Model sequences (1)

XM_001716442.1 PREDICTED: Homo sapiens similar to histone (LOC100133109), mRNA P

EST sequences (10 of 1338) [Show all sequences]

AA954892.1 Clone IMAGE:1576263 intestine 3' read P
AA961103.1 Clone IMAGE:1569812 lung 3' read P
AA968765.1 Clone IMAGE:1597444 uncharacterized tissue 3' read
AA971862.1 Clone IMAGE:1584786 lung 3' read P
AA973697.1 Clone IMAGE:1569088 lung 3' read P
AA974043.1 Clone IMAGE:1585490 lung 3' read P
AA989136.1 Clone IMAGE:1593492 kidney 3' read P
AA988848.1 Clone IMAGE:1602061 lung 3' read P
AA999691.1 Clone IMAGE:1612906 uncharacterized tissue 3' read P
AA907407.1 Clone IMAGE:1521762 lung 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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