ArfGAP with GTPase domain, ankyrin repeat and PH domain 3, Homo sapiens

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
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Highly represented (1.4 pct) in cDNA library dbEST:513, Chromosome 7 Fetal Brain cDNA Library.

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

brain; uncharacterized tissue; eye; lung; embryonic tissue; mixed; testis; mammary gland; kidney; uterus; thyroid; intestine; mouth; thymus; pancreas; ovary; prostate; bone marrow; ear; skin; placenta; trachea; stomach; larynx; blood; ascites; connective tissue; nerve; vascular; salivary gland; cervix; bone; liver; muscle; heart; bladder; adrenal gland; pineal gland

NCBI

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Finding cDNAs

UGID:2477699 UniGene Hs.647075 Homo sapiens (human) AGAP3

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ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 (AGAP3)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
NP_114152.3	centaurin, gamma 3 isoform a	H. sapiens	100.0	910
NP_631892.2	centaurin, gamma 3	M. musculus	98.9	909
NP_001084915.1	hypothetical protein LOC431967	X. laevis	81.4	846
XP_001921526.1	PREDICTED: similar to centaurin, gamma 2	D. rerio	81.0	830
NP_723849.1	centaurin gamma 1A CG31811-PB, isoform B	D. melanogaster	64.4	940
NP_001022837.1	CeNTaurin family member (cnt-2)	C. elegans	51.8	869

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	7
Map position:	7q36.1
UniSTS entry:	Chr 7	(n/a)
UniSTS entry:	Chr 7	RH66056
UniSTS entry:	Chr Y	D8S2278

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

BC044644.1	Homo sapiens centaurin, gamma 3, mRNA (cDNA clone MGC:52327 IMAGE:5453989), complete cds	PA
BC048300.1	Homo sapiens centaurin, gamma 3, mRNA (cDNA clone IMAGE:5517750), partial cds	PA
CR624366.1	full-length cDNA clone CS0DF025YC08 of Fetal brain of Homo sapiens (human)	P
AB209781.1	Homo sapiens mRNA for centaurin, gamma 3 variant protein	P
AL442089.1	Homo sapiens mRNA; cDNA DKFZp761E2216 (from clone DKFZp761E2216)	PA
NM_001042535.1	Homo sapiens ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 (AGAP3), transcript variant 2, mRNA	PA
AK027415.1	Homo sapiens cDNA FLJ14509 fis, clone NT2RM1000499, weakly similar to Caenorhabditis elegans mRNA for centaurin gamma 1A	P
NM_031946.4	Homo sapiens ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 (AGAP3), transcript variant 1, mRNA	PA
AF413079.1	Homo sapiens centaurin gamma3 mRNA, complete cds	P
AK055393.1	Homo sapiens cDNA FLJ30831 fis, clone FEBRA2001989, highly similar to Centaurin-gamma 3	P
AK096352.1	Homo sapiens cDNA FLJ39033 fis, clone NT2RP7007842, weakly similar to Drosophila melanogaster Centaurin Gamma 1A (ceng1A) mRNA	P
AK091771.1	Homo sapiens cDNA FLJ34452 fis, clone HLUNG2002405	A
BC020426.1	Homo sapiens centaurin, gamma 3, mRNA (cDNA clone IMAGE:3857278)	P
BC037543.1	Homo sapiens, Similar to centaurin, gamma 3, clone IMAGE:5183789, mRNA	PA

EST sequences (10 of 400) [Show all sequences]

AI001048.1	Clone IMAGE:1610173	mammary gland	3' read
AI016209.1	Clone IMAGE:1623403	embryonic tissue	3' read	A
AI052382.1	Clone IMAGE:1676168	embryonic tissue	3' read	P
AI077690.1	Clone IMAGE:1664495	skin	3' read	P
AI078119.1	Clone IMAGE:1676276	embryonic tissue	3' read	A
AI095271.1	Clone IMAGE:1666339	skin	3' read	P
BX103340.1	Clone IMAGp998B07312_;_IMAGE:172326	brain
AI206287.1	Clone IMAGE:1942009	uncharacterized tissue	3' read	A
CB125083.1	Clone L5HLK1s1-14-B06	liver	5' read	P
CB151997.1	Clone B1T694954-17-A07	brain	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria