Heat shock 60kDa protein 1 (chaperonin), Homo sapiens

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
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Highly represented (2.3 pct) in cDNA library dbEST:3186, CT0341.

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

liver; embryonic tissue; uncharacterized tissue; tonsil; ascites; placenta; stomach; intestine; bladder; lymph; uterus; ear; brain; adrenal gland; testis; lung; kidney; skin; mammary gland; pancreas; thymus; eye; prostate; mixed; muscle; pituitary gland; ovary; blood; umbilical cord; cervix; thyroid; vascular; bone marrow; connective tissue; lymph node; mouth; nerve; bone; heart; adipose tissue; esophagus

NCBI

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Finding cDNAs

UGID:2064064 UniGene Hs.595053 Homo sapiens (human) HSPD1

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Heat shock 60kDa protein 1 (chaperonin) (HSPD1)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
XP_857282.1	PREDICTED: similar to 60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein) (HuCHA60) isoform 5	C. lupus familiaris	99.3	551
NP_723104.2	Hsp60C CG7235-PA, isoform A	D. melanogaster	79.8	572
NP_175945.1	CPN60B (CHAPERONIN 60 BETA); ATP binding / protein binding / unfolded protein binding	A. thaliana	53.9	544

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	5
	Map position:	2q33.1

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

M34664.1	Human chaperonin (HSP60) mRNA, complete cds	P
BC047350.1	Homo sapiens heat shock 60kDa protein 1 (chaperonin), mRNA (cDNA clone IMAGE:4214709)	PA
BC067082.1	Homo sapiens heat shock 60kDa protein 1 (chaperonin), mRNA (cDNA clone MGC:71259 IMAGE:4025725), complete cds	PA
BC073746.1	Homo sapiens heat shock 60kDa protein 1 (chaperonin), mRNA (cDNA clone MGC:88749 IMAGE:6372068), complete cds	PA
CR621020.1	full-length cDNA clone CS0DC020YN10 of Neuroblastoma Cot 25-normalized of Homo sapiens (human)	P
CR619688.1	full-length cDNA clone CS0DH002YB12 of T cells (Jurkat cell line) of Homo sapiens (human)	P
CR599532.1	full-length cDNA clone CL0BA008ZG11 of Placenta of Homo sapiens (human)	P
CR593187.1	full-length cDNA clone CS0DG003YN06 of B cells (Ramos cell line) of Homo sapiens (human)	P
M22382.1	Human mitochondrial matrix protein P1 (nuclear encoded) mRNA, complete cds	P
BC003030.1	Homo sapiens heat shock 60kDa protein 1 (chaperonin), mRNA (cDNA clone MGC:4335 IMAGE:2821157), complete cds	PA
BC002676.2	Homo sapiens heat shock 60kDa protein 1 (chaperonin), mRNA (cDNA clone MGC:4084 IMAGE:3609039), complete cds	PA
AK312240.1	Homo sapiens cDNA, FLJ92534, highly similar to Homo sapiens heat shock 60kDa protein 1 (chaperonin) (HSPD1), mRNA
EU719626.1	Homo sapiens mitochondrial heat shock 60kD protein 1 variant 1 (HSPD1) mRNA, complete cds, alternatively spliced; nuclear gene for mitochondrial product

EST sequences (10 of 684) [Show all sequences]

CA976084.1	Clone IMAGE:6202494	nerve	5' read	P
CB044501.1	Clone IMAGE:3217787	intestine	5' read	P
CB158602.1	Clone L18POOL1n1-12-B07	liver	5' read	P
CB163428.1	Clone L18POOL1n1-51-G04	liver	5' read	P
CB108400.1	Clone L3SNU475-32-A07	liver	5' read	P
CB107411.1	Clone L3SNU475-21-G06	liver	5' read	P
CB119758.1	Clone L3SNU475s1-16-A10	liver	5' read	P
CB133305.1	Clone L4SNU368s1-20-D10	liver	5' read	P
CB133553.1	Clone L4SNU368s1-7-C02	liver	5' read	P
CB133620.1	Clone L4SNU368s1-14-G03	liver	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria