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UGID:707566     UniGene Hs.492407     Homo sapiens (human)   YWHAZ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (YWHAZ)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_663723.1 tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide H. sapiens 100.0 244
XP_849044.1 PREDICTED: similar to tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide isoform 2 C. lupus familiaris 100.0 244
XP_001493038.1 PREDICTED: similar to tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide E. caballus 100.0 244
NP_509938.2 Fourteen-Three-Three family member (ftt-2) C. elegans 87.9 197
NP_724884.1 14-3-3zeta CG17870-PE, isoform E D. melanogaster 87.5 247
NP_564167.1 GRF10 (GENERAL REGULATORY FACTOR 10); protein phosphorylated amino acid binding A. thaliana 74.1 250

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented in several libraries
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: brain; embryonic tissue; uncharacterized tissue; intestine; uterus; testis; skin; eye; placenta; lung; blood; mammary gland; liver; pancreas; mixed; kidney; mouth; prostate; stomach; lymph node; parathyroid; ascites; ovary; cervix; vascular; heart; thyroid; bone marrow; bladder; pharynx; connective tissue; ear; bone; esophagus; adrenal gland; lymph; adipose tissue; thymus; spleen; muscle; larynx; ganglia; nerve; salivary gland; pituitary gland; trachea; tonsil
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 8
Map position: 8q23.1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (32)

M86400.1 Human phospholipase A2 mRNA, complete cds P
BC051814.1 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide, mRNA (cDNA clone IMAGE:5527579), partial cds PA
NM_003406.2 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (YWHAZ), transcript variant 1, mRNA P
BC063824.1 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide, mRNA (cDNA clone MGC:74590 IMAGE:6180974), complete cds PA
BC068456.1 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide, mRNA (cDNA clone MGC:87045 IMAGE:4793291), complete cds PA
BC070389.1 Homo sapiens cDNA clone IMAGE:4047193, partial cds A
BC072426.1 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide, mRNA (cDNA clone MGC:87788 IMAGE:6315583), complete cds PA
BC073141.1 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide, mRNA (cDNA clone IMAGE:6504109), partial cds PA
CR625952.1 full-length cDNA clone CS0DF029YC05 of Fetal brain of Homo sapiens (human) P
CR624253.1 full-length cDNA clone CS0DG005YN09 of B cells (Ramos cell line) of Homo sapiens (human) P
CR623658.1 full-length cDNA clone CS0DA012YN19 of Neuroblastoma of Homo sapiens (human) P
CR623456.1 full-length cDNA clone CS0DF007YJ11 of Fetal brain of Homo sapiens (human) P
CR614741.1 full-length cDNA clone CS0DG004YE17 of B cells (Ramos cell line) of Homo sapiens (human) P
CR612878.1 full-length cDNA clone CS0DF029YJ15 of Fetal brain of Homo sapiens (human) P
CR611466.1 full-length cDNA clone CS0DF011YI24 of Fetal brain of Homo sapiens (human) P
CR607781.1 full-length cDNA clone CL0BB016ZG01 of Neuroblastoma of Homo sapiens (human)
CR606956.1 full-length cDNA clone CS0DM001YK17 of Fetal liver of Homo sapiens (human) P
BC083508.1 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide, mRNA (cDNA clone MGC:87787 IMAGE:5563061), complete cds PA
BC099904.1 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide, mRNA (cDNA clone MGC:104542 IMAGE:5298373), complete cds PA
BC101483.1 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide, mRNA (cDNA clone MGC:126532 IMAGE:8068989), complete cds P
BC108281.1 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide, mRNA (cDNA clone MGC:111427 IMAGE:3869494), complete cds PA
BC111951.1 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide, transcript variant 2, mRNA (cDNA clone MGC:138156 IMAGE:8327419), complete cds P
DQ185048.1 Homo sapiens tyrosine 3-monooxygenasea/tryptophan 5-monooxygenase activation protein zeta mRNA, partial cds P
BC003623.2 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide, mRNA (cDNA clone MGC:2153 IMAGE:2988020), complete cds PA
AK289945.1 Homo sapiens cDNA FLJ76227 complete cds, highly similar to Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (YWHAZ), transcript variant 1, mRNA
AK307506.1 Homo sapiens cDNA, FLJ97454
AK315867.1 Homo sapiens cDNA, FLJ79516 complete cds, highly similar to 14-3-3 protein zeta/delta
AK091235.1 Homo sapiens cDNA FLJ33916 fis, clone CTONG2016775
NM_145690.1 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (YWHAZ), transcript variant 2, mRNA P
BC013265.1 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide, mRNA (cDNA clone IMAGE:3873977) PA
S79449.1 14-3-3 protein/cytosolic phospholipase A2 [human, lung adenocarcinoma cell line A549, mRNA Partial, 210 nt] P
U28964.1 Homo sapiens 14-3-3 protein mRNA, complete cds P

EST sequences (10 of 1787) [Show all sequences]

AA961128.1 Clone IMAGE:1575526 intestine 3' read A
AA922431.1 Clone IMAGE:1486403 mouth 3' read A
AA969836.1 Clone IMAGE:1575786 intestine 3' read A
AA971870.1 Clone IMAGE:1584787 lung 3' read
AA976715.1 Clone IMAGE:1585551 lung 3' read P
AA976827.1 Clone IMAGE:1588320 uncharacterized tissue 3' read A
AA977867.1 Clone IMAGE:1590342 kidney 3' read A
AA905225.1 Clone IMAGE:1507064 mixed 3' read P
AA905754.1 Clone IMAGE:1504563 mixed 3' read P
AA911031.1 Clone IMAGE:1518473 uncharacterized tissue 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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