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UGID:159178     UniGene Hs.180909     Homo sapiens (human)   PRDX1
Peroxiredoxin 1 (PRDX1)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
XP_001102188.1 PREDICTED: similar to peroxiredoxin 1 isoform 2 M. mulatta 100.0 198
XP_001156454.1 PREDICTED: peroxiredoxin 1 isoform 2 P. troglodytes 100.0 198
NP_859047.1 peroxiredoxin 1 H. sapiens 100.0 198
XP_532599.2 PREDICTED: similar to peroxiredoxin 1 C. lupus familiaris 99.5 198
XP_001496084.1 PREDICTED: similar to peroxiredoxin 1 E. caballus 99.5 198
NP_035164.1 peroxiredoxin 1 M. musculus 97.0 198
NP_001085178.1 hypothetical protein LOC432262 X. laevis 91.5 198
NP_001013489.1 hypothetical protein LOC541344 D. rerio 88.4 198
NP_001122604.1 PeRoxireDoXin family member (prdx-2) C. elegans 82.3 197
NP_477510.1 thioredoxin peroxidase 1 CG1633-PA, isoform A D. melanogaster 78.9 193
XP_001699660.1 2-cys peroxiredoxin C. reinhardtii 76.1 196
NP_013684.1 Ubiquitous housekeeping thioredoxin peroxidase, reduces reactive oxygen, nitrogen and sulfur species using thioredoxin as hydrogen donor; mediates redox regulation of the nuclear localization of Yap1p; deletion results in mutator phenotype; Tsa1p S. cerevisiae 66.2 194
NP_568166.1 2-cys peroxiredoxin, chloroplast, putative A. thaliana 66.0 240

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented (7.0 pct) in cDNA library dbEST:8501, FT0194.
Note: Highly represented (2.9 pct) in cDNA library dbEST:8352, GN0163.
Note: Highly represented (1.1 pct) in cDNA library dbEST:6832, NIH_MGC_61.
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: brain; skin; lung; liver; testis; eye; pancreas; mixed; prostate; embryonic tissue; uncharacterized tissue; placenta; uterus; bladder; intestine; kidney; muscle; ovary; ascites; bone; stomach; cervix; mammary gland; connective tissue; blood; heart; lymph; vascular; bone marrow; pharynx; spleen; salivary gland; larynx; lymph node; thyroid; parathyroid; tonsil; umbilical cord; adrenal gland; pineal gland; epididymis; nerve; mouth; thymus; pituitary gland; spinal cord; amniotic fluid; adipose tissue; esophagus
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p34.1
UniSTS entry: RH70158
UniSTS entry: Chr 1 A007G24
UniSTS entry: Chr 1 SHGC-132089
UniSTS entry: Chr 1 D1S2391
UniSTS entry: (n/a)
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

NM_181697.1 Homo sapiens peroxiredoxin 1 (PRDX1), transcript variant 3, mRNA PA
NM_181696.1 Homo sapiens peroxiredoxin 1 (PRDX1), transcript variant 2, mRNA PA
AK131049.1 Homo sapiens cDNA FLJ29015 fis, clone MPE08581, highly similar to Peroxiredoxin 1 P
L19184.1 Human natural killer cell enhancing factor (NKEFA) mRNA, complete cds P
NM_002574.2 Homo sapiens peroxiredoxin 1 (PRDX1), transcript variant 1, mRNA PA
CR407652.1 Homo sapiens full open reading frame cDNA clone RZPDo834H022D for gene PRDX1, peroxiredoxin 1 complete cds, without stopcodon P
CR620467.1 full-length cDNA clone CS0DH005YP04 of T cells (Jurkat cell line) of Homo sapiens (human) P
CR612185.1 full-length cDNA clone CS0DC013YL24 of Neuroblastoma Cot 25-normalized of Homo sapiens (human) P
CR595111.1 full-length cDNA clone CS0DG003YF19 of B cells (Ramos cell line) of Homo sapiens (human) P
CR593924.1 full-length cDNA clone CS0DC014YE06 of Neuroblastoma Cot 25-normalized of Homo sapiens (human) P
CR592546.1 full-length cDNA clone CS0DM012YB22 of Fetal liver of Homo sapiens (human) P
BT019740.1 Homo sapiens peroxiredoxin 1 mRNA, complete cds P
BC007063.1 Homo sapiens peroxiredoxin 1, mRNA (cDNA clone MGC:12514 IMAGE:3961375), complete cds PA
BC021683.1 Homo sapiens peroxiredoxin 1, mRNA (cDNA clone MGC:24196 IMAGE:3681912), complete cds PA
AK311898.1 Homo sapiens cDNA, FLJ92164, highly similar to Homo sapiens peroxiredoxin 1 (PRDX1), mRNA P
AB451388.1 Homo sapiens PRDX1 mRNA for peroxiredoxin 1, partial cds, clone: FLJ08078AAAF P
AB451262.1 Homo sapiens PRDX1 mRNA for peroxiredoxin 1, complete cds, clone: FLJ08078AAAN P
X67951.1 H.sapiens mRNA for proliferation-associated gene (pag) P

EST sequences (10 of 2827) [Show all sequences]

AA961338.1 Clone IMAGE:1599458 uncharacterized tissue 3' read P
AA962157.1 Clone IMAGE:1553461 kidney 3' read A
AA976529.1 Clone IMAGE:1587862 uncharacterized tissue 3' read A
AA984482.1 Clone IMAGE:1630102 brain 3' read P
AA991862.1 Clone IMAGE:1610466 uncharacterized tissue 3' read A
AA994772.1 Clone IMAGE:1631281 mammary gland 3' read
AA995421.1 Clone IMAGE:1612042 uncharacterized tissue 3' read
AA906811.1 Clone IMAGE:1519588 uncharacterized tissue 3' read P
AI022107.1 Clone IMAGE:1650855 parathyroid 3' read P
AI031932.1 Clone IMAGE:1650011 parathyroid 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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