Guanine nucleotide binding protein (G protein), beta polypeptide 1, Homo sapiens

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
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Highly represented (1.3 pct) in cDNA library dbEST:3317, HT0198.

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

brain; lung; eye; uncharacterized tissue; uterus; skin; testis; embryonic tissue; intestine; prostate; mixed; pancreas; placenta; liver; blood; ovary; mouth; heart; muscle; thyroid; connective tissue; parathyroid; pituitary gland; mammary gland; esophagus; tonsil; ascites; lymph; bone; kidney; stomach; amniotic fluid; bone marrow; vascular; thymus; lymph node; adrenal gland; bladder; ganglia; larynx; spleen; cervix; pineal gland; pharynx; salivary gland; spinal cord; nerve

NCBI

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Finding cDNAs

UGID:3321415 UniGene Hs.709208 Homo sapiens (human) GNB1

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Guanine nucleotide binding protein (G protein), beta polypeptide 1 (GNB1)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
NP_112249.2	guanine nucleotide-binding protein, beta-1 subunit	R. norvegicus	100.0	339
NP_727907.1	G protein beta-subunit 13F CG10545-PB, isoform B	D. melanogaster	88.5	339
XP_001005405.1	PREDICTED: similar to ribosomal protein L24	M. musculus	65.5	87
NP_006569.1	guanine nucleotide-binding protein, beta-5 subunit isoform a	H. sapiens	58.5	342
NP_974683.1	AGB1 (GTP BINDING PROTEIN BETA 1); nucleotide binding	A. thaliana	50.8	323

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	1
	Map position:	1p36.33

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (20)

AF070597.1	Homo sapiens clone 24596 beta-subunit signal transducing proteins GS/GI mRNA, partial cds	PA
AF070603.1	Homo sapiens clone 24584 beta-subunit signal transducing proteins GS/GI mRNA, partial cds	PA
BT007305.1	Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 1 mRNA, complete cds	P
AK122949.1	Homo sapiens cDNA FLJ16663 fis, clone THYMU2005759, highly similar to Guanine nucleotide-binding proteinG(I)/G(S)/G(T) subunit beta 1	P
CR456784.1	Homo sapiens full open reading frame cDNA clone RZPDo834G064D for gene GNB1, guanine nucleotide binding protein (G protein), beta polypeptide 1; complete cds, incl. stopcodon	P
CR623427.1	full-length cDNA clone CS0DF009YP24 of Fetal brain of Homo sapiens (human)	P
CR619305.1	full-length cDNA clone CS0DG003YI23 of B cells (Ramos cell line) of Homo sapiens (human)	P
CR606385.1	full-length cDNA clone CS0DA004YO10 of Neuroblastoma of Homo sapiens (human)
CR595196.1	full-length cDNA clone CS0DJ014YB19 of T cells (Jurkat cell line) Cot 10-normalized of Homo sapiens (human)	P
CR592893.1	full-length cDNA clone CS0DA001YO14 of Neuroblastoma of Homo sapiens (human)	P
CR591784.1	full-length cDNA clone CS0DI001YP06 of Placenta Cot 25-normalized of Homo sapiens (human)	P
NM_002074.2	Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 1 (GNB1), mRNA	PA
BC114618.1	Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 1, mRNA (cDNA clone IMAGE:40032959), partial cds	P
BC004186.2	Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 1, mRNA (cDNA clone MGC:2819 IMAGE:2964393), complete cds	PA
BC005888.2	Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 1, mRNA (cDNA clone MGC:4855 IMAGE:3605228), complete cds	PA
BC008991.1	Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 1, mRNA (cDNA clone MGC:18208 IMAGE:4155946), complete cds	PA
M36430.1	Human transducin beta-1 subunit mRNA, 3' end	P
AK312614.1	Homo sapiens cDNA, FLJ92996, highly similar to Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 1 (GNB1), mRNA
AF501882.1	Homo sapiens guanine nucleotide binding protein beta 1 (GNB1) mRNA, complete cds	P
AK096614.1	Homo sapiens cDNA FLJ39295 fis, clone OCBBF2012714, highly similar to GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(T) BETA SUBUNIT 1

EST sequences (10 of 1203) [Show all sequences]

AA969550.1	Clone IMAGE:1576311	intestine	3' read	A
AA970412.1	Clone IMAGE:1573066	kidney	3' read	A
R15965.1	Clone IMAGE:53142	brain	5' read
AA975439.1	Clone IMAGE:1558158	lung	3' read	A
R14688.1	Clone IMAGE:30267	brain	5' read
AA988849.1	Clone IMAGE:1602063	lung	3' read	A
AA993766.1	Clone IMAGE:1621694	testis	3' read	A
AA995318.1	Clone IMAGE:1606607	kidney	3' read	A
AA907565.1	Clone IMAGE:1540558	mixed	3' read
AI018022.1	Clone IMAGE:1642066	testis	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria