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UGID:148528     UniGene Hs.129673     Homo sapiens (human)   EIF4A1
Eukaryotic translation initiation factor 4A, isoform 1 (EIF4A1)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_001093666.1 eukaryotic translation initiation factor 4A isoform 1 S. scrofa 100.0 405
XP_001109752.1 PREDICTED: similar to eukaryotic translation initiation factor 4A, isoform 1 isoform 3 M. mulatta 100.0 389
XP_536623.2 PREDICTED: similar to eukaryotic translation initiation factor 4A, isoform 1 isoform 1 C. lupus familiaris 100.0 389
NP_001116510.1 eukaryotic translation initiation factor 4A2 isoform c M. musculus 96.1 361
NP_001022624.1 INitiation Factor family member (inf-1) C. elegans 89.6 114
NP_723137.1 Eukaryotic initiation factor 4a CG9075-PA, isoform A D. melanogaster 82.8 401
NP_001030693.1 EIF4A1 (eukaryotic translation initiation factor 4A-1); ATP-dependent helicase A. thaliana 79.7 399
XP_961600.1 eukaryotic initiation factor 4A-12 N. crassa 76.9 399

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented in several libraries
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: brain; lung; embryonic tissue; pancreas; skin; liver; placenta; uncharacterized tissue; uterus; intestine; testis; prostate; eye; mammary gland; kidney; cervix; stomach; lymph; ascites; ovary; blood; bone; connective tissue; mixed; muscle; thymus; heart; bone marrow; vascular; spleen; lymph node; adrenal gland; salivary gland; thyroid; esophagus; bladder; larynx; tonsil; umbilical cord; pharynx; mouth; parathyroid; nerve; adipose tissue; trachea; pituitary gland; ganglia; epididymis; ear; amniotic fluid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17p13
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (57)

AK130082.1 Homo sapiens cDNA FLJ26572 fis, clone LNF05779, highly similar to Eukaryotic initiation factor 4A-I (eIF-4A-I) P
NM_001416.2 Homo sapiens eukaryotic translation initiation factor 4A, isoform 1 (EIF4A1), mRNA
AJ609447.1 Homo sapiens ACA48 snoRNA gene
BC073752.1 Homo sapiens eukaryotic translation initiation factor 4A, isoform 1, mRNA (cDNA clone MGC:88756 IMAGE:6371531), complete cds PA
CR626851.1 full-length cDNA clone CS0DF019YF06 of Fetal brain of Homo sapiens (human) P
CR624603.1 full-length cDNA clone CS0DM001YP05 of Fetal liver of Homo sapiens (human) P
CR623219.1 full-length cDNA clone CL0BB009ZA08 of Neuroblastoma of Homo sapiens (human) P
CR623167.1 full-length cDNA clone CS0DK004YO11 of HeLa cells Cot 25-normalized of Homo sapiens (human) A
CR623095.1 full-length cDNA clone CS0DF003YE17 of Fetal brain of Homo sapiens (human) P
CR622601.1 full-length cDNA clone CS0DF032YG04 of Fetal brain of Homo sapiens (human) P
CR621511.1 full-length cDNA clone CS0DH007YM23 of T cells (Jurkat cell line) of Homo sapiens (human) P
CR621238.1 full-length cDNA clone CS0DA004YK05 of Neuroblastoma of Homo sapiens (human) P
CR620740.1 full-length cDNA clone CS0DA006YA19 of Neuroblastoma of Homo sapiens (human) P
CR619751.1 full-length cDNA clone CS0DF001YB06 of Fetal brain of Homo sapiens (human) P
CR619465.1 full-length cDNA clone CS0DH002YB19 of T cells (Jurkat cell line) of Homo sapiens (human) P
CR618674.1 full-length cDNA clone CS0DK008YE05 of HeLa cells Cot 25-normalized of Homo sapiens (human) P
CR617051.1 full-length cDNA clone CS0DH001YG02 of T cells (Jurkat cell line) of Homo sapiens (human) P
CR614903.1 full-length cDNA clone CS0DF007YF10 of Fetal brain of Homo sapiens (human) P
CR612440.1 full-length cDNA clone CS0DA006YH16 of Neuroblastoma of Homo sapiens (human) P
CR610019.1 full-length cDNA clone CS0DA009YG22 of Neuroblastoma of Homo sapiens (human) P
CR608998.1 full-length cDNA clone CS0DI002YI16 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR607537.1 full-length cDNA clone CS0DI058YE08 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR605465.1 full-length cDNA clone CS0DF002YB24 of Fetal brain of Homo sapiens (human) P
CR605316.1 full-length cDNA clone CS0DF008YL04 of Fetal brain of Homo sapiens (human) P
CR604267.1 full-length cDNA clone CS0DH002YN10 of T cells (Jurkat cell line) of Homo sapiens (human) P
CR603854.1 full-length cDNA clone CS0DH004YM20 of T cells (Jurkat cell line) of Homo sapiens (human) P
CR603368.1 full-length cDNA clone CS0DI020YH17 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR602368.1 full-length cDNA clone CS0DF036YA10 of Fetal brain of Homo sapiens (human) P
CR602367.1 full-length cDNA clone CS0DF022YP15 of Fetal brain of Homo sapiens (human) P
CR600480.1 full-length cDNA clone CS0DA009YG09 of Neuroblastoma of Homo sapiens (human) P
CR600142.1 full-length cDNA clone CS0CAP004YH19 of Thymus of Homo sapiens (human) P
CR599522.1 full-length cDNA clone CS0DE008YL11 of Placenta of Homo sapiens (human) P
CR599489.1 full-length cDNA clone CS0DI057YL14 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR599025.1 full-length cDNA clone CS0DA009YA04 of Neuroblastoma of Homo sapiens (human) P
CR598780.1 full-length cDNA clone CS0DH005YE18 of T cells (Jurkat cell line) of Homo sapiens (human) P
CR598002.1 full-length cDNA clone CS0DI068YH02 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR596028.1 full-length cDNA clone CL0BA005ZH08 of Placenta of Homo sapiens (human) P
CR592725.1 full-length cDNA clone CS0DI009YB15 of Placenta Cot 25-normalized of Homo sapiens (human) P
BT019881.1 Homo sapiens eukaryotic translation initiation factor 4A, isoform 1 mRNA, complete cds P
BT019880.1 Homo sapiens eukaryotic translation initiation factor 4A, isoform 1 mRNA, complete cds P
NR_002604.2 Homo sapiens small nucleolar RNA, C/D box 10 (SNORD10) on chromosome 17
NR_002918.1 Homo sapiens small nucleolar RNA, H/ACA box 48 (SNORA48) on chromosome 17
NR_002912.1 Homo sapiens small nucleolar RNA, H/ACA box 67 (SNORA67) on chromosome 17
BC006210.2 Homo sapiens eukaryotic translation initiation factor 4A, isoform 1, mRNA (cDNA clone IMAGE:2821876), partial cds PA
BC009585.1 Homo sapiens eukaryotic translation initiation factor 4A, isoform 1, mRNA (cDNA clone MGC:14648 IMAGE:4096621), complete cds PA
AK289453.1 Homo sapiens cDNA FLJ78614 complete cds, highly similar to Homo sapiens eukaryotic translation initiation factor 4A, isoform 1 (EIF4A1), mRNA
AK291971.1 Homo sapiens cDNA FLJ78244 complete cds, highly similar to Homo sapiens eukaryotic translation initiation factor 4A, isoform 1 (EIF4A1), mRNA
AK312630.1 Homo sapiens cDNA, FLJ93014, Homo sapiens eukaryotic translation initiation factor 4A, isoform 1(EIF4A1), mRNA
AK309274.1 Homo sapiens cDNA, FLJ99315
AK297916.1 Homo sapiens cDNA FLJ58596 complete cds, highly similar to Eukaryotic initiation factor 4A-I (EC 3.6.1.-)
AK296664.1 Homo sapiens cDNA FLJ58012 complete cds, moderately similar to Eukaryotic initiation factor 4A-I (EC 3.6.1.-)
AK303599.1 Homo sapiens cDNA FLJ57766 complete cds, moderately similar to Eukaryotic initiation factor 4A-I (EC 3.6.1.-)
AK303222.1 Homo sapiens cDNA FLJ59127 complete cds, highly similar to Eukaryotic initiation factor 4A-I (EC 3.6.1.-)
BC032078.1 Homo sapiens eukaryotic translation initiation factor 4A, isoform 1, mRNA (cDNA clone IMAGE:3880019) PA
Y11161.1 H.sapiens U67 small nucleolar RNA gene
U79273.1 Human clone 23933 mRNA sequence A
D13748.1 Homo sapiens mRNA for eukaryotic initiation factor 4AI, complete cds P

EST sequences (10 of 5481) [Show all sequences]

AA961718.1 Clone IMAGE:1598349 uncharacterized tissue 3' read A
AA970221.1 Clone IMAGE:1575173 kidney 3' read
AA970752.1 Clone IMAGE:1576454 intestine 3' read A
AA970810.1 Clone IMAGE:1576512 intestine 3' read A
R14761.1 Clone IMAGE:30171 brain 5' read P
AA983521.1 Clone IMAGE:1598461 uncharacterized tissue 3' read PA
AA983725.1 Clone IMAGE:1490873 skin 3' read A
AA993192.1 Clone IMAGE:1624319 embryonic tissue 3' read PA
AA886411.1 Clone IMAGE:1500673 kidney 3' read A
AI002526.1 Clone IMAGE:1594247 kidney 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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