Eukaryotic translation initiation factor 4H, Homo sapiens

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]

Highly represented (2.0 pct) in cDNA library dbEST:6397, FN0181.

Highly represented (1.8 pct) in cDNA library dbEST:3876, PT0009.

Highly represented (1.7 pct) in cDNA library dbEST:4191, UM0051.

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

uncharacterized tissue; brain; lung; skin; placenta; embryonic tissue; eye; uterus; pancreas; intestine; muscle; mixed; kidney; prostate; lymph; testis; mammary gland; stomach; bladder; heart; connective tissue; vascular; amniotic fluid; pineal gland; larynx; bone; liver; lymph node; blood; ovary; cervix; bone marrow; parathyroid; tonsil; thymus; adipose tissue; nerve; adrenal gland; ascites; mouth; pituitary gland; ganglia; thyroid; pharynx; salivary gland; ear; umbilical cord; spleen; epididymis

NCBI

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Finding cDNAs

UGID:911690 UniGene Hs.520943 Homo sapiens (human) EIF4H

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Eukaryotic translation initiation factor 4H (EIF4H)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
NP_291039.1	eukaryotic translation initiation factor 4H	M. musculus	100.0	247
XP_001082007.1	PREDICTED: similar to Eukaryotic translation initiation factor 4H (eIF-4H) (Williams-Beuren syndrome chromosome region 1 protein homolog)	M. mulatta	100.0	247
XP_001148962.1	PREDICTED: similar to Wbscr1 isoform 1	P. troglodytes	100.0	247
NP_071496.1	eukaryotic translation initiation factor 4H isoform 1	H. sapiens	100.0	247
NP_001069220.1	eukaryotic translation initiation factor 4H	B. taurus	100.0	227
NP_001006958.1	eukaryotic translation initiation factor 4H	R. norvegicus	99.6	247
NP_991258.1	hypothetical protein LOC402996	D. rerio	85.2	262
NP_001087148.1	Williams-Beuren syndrome chromosome region 1	X. laevis	84.8	249
NP_727982.1	RNA-binding protein 2 CG4429-PB, isoform B	D. melanogaster	47.6	315

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	7
Map position:	7q11.23
UniSTS entry:	Chr 7	RH40639
UniSTS entry:	Chr 7	(n/a)
UniSTS entry:	Chr 7	SHGC-5607
UniSTS entry:	Chr 7	D7S3017E
UniSTS entry:	Chr 2	RH69870

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (25)

BC066928.1	Homo sapiens eukaryotic translation initiation factor 4H, mRNA (cDNA clone MGC:87218 IMAGE:5263716), complete cds	PA
CR623691.1	full-length cDNA clone CS0DI013YC23 of Placenta Cot 25-normalized of Homo sapiens (human)
CR621172.1	full-length cDNA clone CS0DI068YH12 of Placenta Cot 25-normalized of Homo sapiens (human)	P
CR621128.1	full-length cDNA clone CS0DE008YI01 of Placenta of Homo sapiens (human)	P
CR617014.1	full-length cDNA clone CS0DG001YH18 of B cells (Ramos cell line) of Homo sapiens (human)
CR615480.1	full-length cDNA clone CS0DA009YL19 of Neuroblastoma of Homo sapiens (human)	P
CR614031.1	full-length cDNA clone CS0DB006YP11 of Neuroblastoma Cot 10-normalized of Homo sapiens (human)	P
CR611374.1	full-length cDNA clone CS0DF002YG15 of Fetal brain of Homo sapiens (human)
CR610962.1	full-length cDNA clone CS0DI058YA02 of Placenta Cot 25-normalized of Homo sapiens (human)	P
CR608535.1	full-length cDNA clone CS0DI059YH09 of Placenta Cot 25-normalized of Homo sapiens (human)	P
CR602647.1	full-length cDNA clone CS0DI029YB18 of Placenta Cot 25-normalized of Homo sapiens (human)
CR599953.1	full-length cDNA clone CS0DI041YM12 of Placenta Cot 25-normalized of Homo sapiens (human)	P
CR599580.1	full-length cDNA clone CS0DI079YK20 of Placenta Cot 25-normalized of Homo sapiens (human)	P
CR595546.1	full-length cDNA clone CS0DN005YI07 of Adult brain of Homo sapiens (human)	P
CR595248.1	full-length cDNA clone CS0DG004YB19 of B cells (Ramos cell line) of Homo sapiens (human)	P
CR595117.1	full-length cDNA clone CS0DA004YF10 of Neuroblastoma of Homo sapiens (human)	P
CR593131.1	full-length cDNA clone CS0DI034YC01 of Placenta Cot 25-normalized of Homo sapiens (human)	P
NM_022170.1	Homo sapiens eukaryotic translation initiation factor 4H (EIF4H), transcript variant 1, mRNA	P
BC010021.1	Homo sapiens eukaryotic translation initiation factor 4H, mRNA (cDNA clone MGC:19645 IMAGE:2960402), complete cds	PA
NM_031992.1	Homo sapiens eukaryotic translation initiation factor 4H (EIF4H), transcript variant 2, mRNA	P
BC021214.2	Homo sapiens eukaryotic translation initiation factor 4H, mRNA (cDNA clone MGC:12890 IMAGE:4139578), complete cds	PA
AK290676.1	Homo sapiens cDNA FLJ75661 complete cds, highly similar to Homo sapiens Williams-Beuren syndrome chromosome region 1 (WBSCR1), transcript variant 2, mRNA	P
AK314749.1	Homo sapiens cDNA, FLJ95613	P
D26068.1	Homo sapiens KIAA0038 mRNA, partial cds	P
AK297651.1	Homo sapiens cDNA FLJ60708 complete cds, highly similar to Eukaryotic translation initiation factor 4H	P

EST sequences (10 of 1606) [Show all sequences]

R14046.1	Clone IMAGE:26930	brain	5' read
AA961342.1	Clone IMAGE:1599466	uncharacterized tissue	3' read	A
AA976895.1	Clone IMAGE:1588352	uncharacterized tissue	3' read	P
R15133.1	Clone IMAGE:29737	brain	5' read
AA989595.1	Clone IMAGE:1577354	spleen	3' read	A
AA834197.1	Clone IMAGE:1421185	kidney
AA838444.1	Clone IMAGE:1422568	kidney
R17129.1	Clone IMAGE:31981	brain	5' read
AA907302.1	Clone IMAGE:1521937	lung	3' read	A
AI003926.1	Clone IMAGE:1621862	testis	3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria