Transforming growth factor, beta 1, Homo sapiens

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
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Highly represented (3.0 pct) in cDNA library dbEST:9365, MT0262.

Highly represented (1.8 pct) in cDNA library dbEST:1899, HT0023.

Highly represented (1.0 pct) in cDNA library dbEST:8326, GN0123.

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

uncharacterized tissue; blood; placenta; heart; brain; tonsil; larynx; amniotic fluid; kidney; uterus; connective tissue; mixed; spleen; adipose tissue; eye; liver; salivary gland; bone; pancreas; lung; skin; prostate; lymph; thyroid; embryonic tissue; cervix; mammary gland; intestine; pituitary gland; stomach; pharynx; mouth; bone marrow; testis; epididymis; ovary; ascites; lymph node; umbilical cord; muscle; adrenal gland

NCBI

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Finding cDNAs

UGID:2394304 UniGene Hs.645227 Homo sapiens (human) TGFB1

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Transforming growth factor, beta 1 (TGFB1)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
XP_001161481.1	PREDICTED: hypothetical protein isoform 1	P. troglodytes	59.4	403
XP_854119.1	PREDICTED: similar to Transforming growth factor beta 3 precursor (TGF-beta 3) isoform 2	C. lupus familiaris	58.9	403
NP_653333.1	heterogeneous nuclear ribonucleoprotein U-like 1 isoform d	H. sapiens	49.6	276

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	19
	Map position:	19q13.2\|19q13.1

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

BT007245.1	Homo sapiens transforming growth factor, beta 1 (Camurati-Engelmann disease) mRNA, complete cds	P
M38449.1	Homo sapiens transforming growth factor-beta (TGF-beta) mRNA, partial cds	P
CR612251.1	full-length cDNA clone CS0DD009YM06 of Neuroblastoma Cot 50-normalized of Homo sapiens (human)	P
CR601792.1	full-length cDNA clone CS0DL010YL07 of B cells (Ramos cell line) Cot 25-normalized of Homo sapiens (human)	P
CR592182.1	full-length cDNA clone CS0DC005YF22 of Neuroblastoma Cot 25-normalized of Homo sapiens (human)	P
AY820829.1	Homo sapiens transforming growth factor beta 1 mRNA, partial cds
NM_000660.3	Homo sapiens transforming growth factor, beta 1 (TGFB1), mRNA	P
BC001180.1	Homo sapiens transforming growth factor, beta 1, mRNA (cDNA clone MGC:2323 IMAGE:3356605), complete cds	PA
BC000125.1	Homo sapiens transforming growth factor, beta 1, mRNA (cDNA clone MGC:3119 IMAGE:3351664), complete cds	PA
X02812.1	Human mRNA for transforming growth factor-beta (TGF-beta)	P
BC022242.1	Homo sapiens transforming growth factor, beta 1, mRNA (cDNA clone MGC:22008 IMAGE:4399762), complete cds	PA
AK291907.1	Homo sapiens cDNA FLJ75750 complete cds, highly similar to Homo sapiens transforming growth factor, beta 1 (Camurati-Engelmanndisease) (TGFB1), mRNA	A
AK307742.1	Homo sapiens cDNA, FLJ97690

EST sequences (10 of 421) [Show all sequences]

AA927529.1	Clone IMAGE:1552604	uncharacterized tissue	3' read	A
AI089904.1	Clone IMAGE:1686902	brain	3' read	PA
AI131171.1	Clone IMAGE:1709684	heart	3' read	PA
AI148173.1	Clone IMAGE:1704097	brain	3' read	PA
R24913.1	Clone IMAGE:132031	placenta	5' read
BX097979.1	Clone IMAGp998J22196_;_IMAGE:136821	placenta		P
CB121124.1	Clone L10ChoCK0-29-B08	liver	5' read
CB148401.1	Clone L15CKK1-37-C06	liver	5' read
CB148608.1	Clone L15CKK1-42-H04	liver	5' read
AI272940.1	Clone IMAGE:1876368	mixed	3' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria