Experimental Therapeutics

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Sources of Mouse Models
NCI’s Mouse Repository
Mutant Mouse Regional Resource Centers (MMRRC)
The Jackson Laboratory

Tools for Mouse Modelers
Cancer Model Database (caMOD)
Cancer Image Database (caIMAGE)
caELMIR
Cancer Array Informatics (caArray)
Cancer Biomedical Informatics Grid (caBIG™)
Mouse Genome Informatics (MGI)
Cancer Genome Anatomy Project (CGAP)

Related Links
NCI Center for Bioinformatics (NCICB)
Specialized Programs of Research Excellence (SPORE)
National Center for Biotechnology Information (NCBI)
The Integrative Cancer Biology Program (ICBP)

Emice > Experimental Therapeutics :

Trials

Preclinical Trials
Links to website information about various aspects of preclinical trial experiments:

NCI’s Cancer Models Database (caMOD): data from preclinical trials using animal models ( https://webarchive.library.unt.edu/eot2008/20090131100926/http://cancermodels.nci.nih.gov/)
NCI’s Center for Cancer Research and the Comparative Oncology Program: design, implementation and management of pre-clinical trials (https://webarchive.library.unt.edu/eot2008/20090131100926/http://ccr.cancer.gov/resources/cop/)
caELMIR is a laboratory information management system for the preclinical trials conducted by MMHCC member laboratories (https://webarchive.library.unt.edu/eot2008/20090131100926/http://caelmir.compmed.ucdavis.edu/caelmir/)

Clinical Trials
Website links about to information about clinical trials:

NCI’s clinical trials (https://webarchive.library.unt.edu/eot2008/20090131100926/http://www.cancer.gov/clinicaltrials)
ClinicalTrials.gov provides regularly updated information about federally and privately supported clinical research in humans. (https://webarchive.library.unt.edu/eot2008/20090131100926/http://www.clinicaltrials.gov/)
Industry-sponsored clinical trials (https://webarchive.library.unt.edu/eot2008/20090131100926/http://www.roche-trials.com/index.html)
The Clinical Trial Management Systems Workspace is developing a comprehensive set of modular, interoperable and standards based tools designed to meet the diverse clinical trials management needs of the Cancer Center Community.
The caMOD Drug Screening Search allows querying for the results of a specific compound used in yeast screening, in-vivo screening, pre-clinical trials and in clinical trials. The yeast and in-vivo screening data were obtained from the NCI Developmental Therapeutics Program (https://webarchive.library.unt.edu/eot2008/20090131100926/http://cancermodels.nci.nih.gov/camod/searchDrugScreening.do)
NCI Division of Cancer Treatment and Diagnosis
FDA Oncology Tools

Mammalian Orthology
In this section, you will find links to these websites:

National Center for Biotechnology Information features comparative maps, HomoloGene - a system for automated detection of homologs among the annotated genes of several completely sequenced eukaryotic genomes, TaxPlot (human,mouse,rat) - a tool to compare the similarity of proteins of one genome (the query) to those of two other species and COGs/KOGs - Clusters of Orthologous Groups / euKaryotic Orthologous Groups PubMed.
National Center for Research Resources includes information about the Division of Comparative Medicine which helps to meet the needs of biomedical researchers for high-quality, disease-free animals and specialized animal research facilities.
Rat Genome Database which houses the Virtual Comparative Map tool was developed to explore these syntenic relationships between Rat, Mouse and Human.
Genome Maps (National Cancer Biotechnology Information)
Virtual Comparative Maps (Rat Genome Database Virtual Comparative Maps)
Comparative Medicine (National Center for Research Resources)

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