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UGID:200690     UniGene Hs.374477     Homo sapiens (human)   EWSR1
Ewing sarcoma breakpoint region 1 (EWSR1)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
XP_001104497.1 PREDICTED: similar to RNA-binding protein EWS isoform 4 M. mulatta 100.0 660
XP_001173085.1 PREDICTED: similar to Ewing sarcoma breakpoint region 1 isoform 2 P. troglodytes 100.0 660
NP_005234.1 Ewing sarcoma breakpoint region 1 isoform EWS H. sapiens 100.0 655
XP_864960.1 PREDICTED: similar to RNA-binding protein EWS isoform 10 C. lupus familiaris 99.8 660
XP_001928643.1 PREDICTED: similar to mCG14699 S. scrofa 99.7 353
XP_880795.2 PREDICTED: similar to Ewing sarcoma breakpoint region 1 isoform 8 B. taurus 99.7 660
XP_001068534.1 PREDICTED: similar to Ewing sarcoma breakpoint region 1 isoform EWS isoform 5 R. norvegicus 99.5 655
NP_031994.2 Ewing sarcoma breakpoint region 1 M. musculus 99.4 654
NP_001089902.1 hypothetical protein LOC734969 X. laevis 79.2 666
NP_001108610.1 Ewing sarcoma breakpoint region 1a D. rerio 69.5 625
NP_727946.1 cabeza CG3606-PA, isoform A D. melanogaster 47.7 397

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Expression Profile: View expression levels using UniGene's EST ProfileViewer
[Show more entries with profiles like this]
Note: Highly represented (1.7 pct) in cDNA library dbEST:8501, FT0194.
Note: Highly represented (1.3 pct) in cDNA library dbEST:9495, RT0026.
GEO profiles: Gene expression profiles in the NCBI Gene Expression Omnibus database
cDNA Sources: brain; uncharacterized tissue; placenta; embryonic tissue; testis; uterus; eye; skin; kidney; intestine; blood; liver; lung; muscle; thymus; mixed; prostate; lymph; connective tissue; pancreas; vascular; spleen; mammary gland; cervix; lymph node; heart; mouth; adrenal gland; stomach; bone marrow; tonsil; trachea; ovary; bladder; ascites; bone; larynx; thyroid; ear; salivary gland; pharynx; nerve; pituitary gland; ganglia; adipose tissue; esophagus; umbilical cord
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 22
Map position: 22q12.2
UniSTS entry: GDB:452619
UniSTS entry: (n/a)
UniSTS entry: Chr 22 G06555
UniSTS entry: Chr 22 SGC38366
UniSTS entry: Chr 22 SHGC-37092
UniSTS entry: Chr 22 STS-N54946
UniSTS entry: STS-N54946
UniSTS entry: (n/a)
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (31)

BX648769.1 Homo sapiens mRNA; cDNA DKFZp686M2044 (from clone DKFZp686M2044) PA
AK127624.1 Homo sapiens cDNA FLJ45722 fis, clone HCASM2008154, weakly similar to RNA-binding protein EWS P
NM_005243.2 Homo sapiens Ewing sarcoma breakpoint region 1 (EWSR1), transcript variant EWS, mRNA P
CR456490.1 Homo sapiens EWSR1 full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.EWSR1) P
BC072442.1 Homo sapiens Ewing sarcoma breakpoint region 1, mRNA (cDNA clone MGC:87992 IMAGE:6047805), complete cds PA
CR625247.1 full-length cDNA clone CS0DE005YF11 of Placenta of Homo sapiens (human) P
CR619493.1 full-length cDNA clone CS0DI076YO21 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR618632.1 full-length cDNA clone CS0CAP007YI20 of Thymus of Homo sapiens (human) P
CR617490.1 full-length cDNA clone CS0DB004YG15 of Neuroblastoma Cot 10-normalized of Homo sapiens (human) P
CR610888.1 full-length cDNA clone CS0DF037YI07 of Fetal brain of Homo sapiens (human) P
CR608666.1 full-length cDNA clone CS0DG004YL23 of B cells (Ramos cell line) of Homo sapiens (human) P
CR608375.1 full-length cDNA clone CS0DI039YJ24 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR604952.1 full-length cDNA clone CS0DI010YI12 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR604639.1 full-length cDNA clone CS0DJ013YN08 of T cells (Jurkat cell line) Cot 10-normalized of Homo sapiens (human) P
CR602561.1 full-length cDNA clone CS0DI068YN23 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR594868.1 full-length cDNA clone CS0DI064YE15 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR593724.1 full-length cDNA clone CS0DI011YO05 of Placenta Cot 25-normalized of Homo sapiens (human) P
NM_013986.2 Homo sapiens Ewing sarcoma breakpoint region 1 (EWSR1), transcript variant EWS-b, mRNA P
AK026270.1 Homo sapiens cDNA: FLJ22617 fis, clone HSI05379, highly similar to HSEWS Homo sapiens EWS mRNA PA
BC000527.2 Homo sapiens Ewing sarcoma breakpoint region 1, mRNA (cDNA clone MGC:8607 IMAGE:2961279), complete cds PA
AK225102.1 Homo sapiens mRNA for Ewing sarcoma breakpoint region 1 isoform EWS variant, clone: CAS09229 PA
AK225096.1 Homo sapiens mRNA for Ewing sarcoma breakpoint region 1 isoform EWS variant, clone: CAS06131 PA
BC004817.1 Homo sapiens Ewing sarcoma breakpoint region 1, mRNA (cDNA clone MGC:5432 IMAGE:3449145), complete cds PA
BC011048.1 Homo sapiens Ewing sarcoma breakpoint region 1, mRNA (cDNA clone MGC:16900 IMAGE:4340116), complete cds PA
AK056681.1 Homo sapiens cDNA FLJ32119 fis, clone PEBLM1000034, highly similar to RNA-BINDING PROTEIN EWS P
AK056309.1 Homo sapiens cDNA FLJ31747 fis, clone NT2RI2007377, highly similar to RNA-BINDING PROTEIN EWS PA
EU327511.1 Homo sapiens EWSR1/ZNF384 fusion protein (EWSR1/ZNF384 fusion) mRNA, partial cds P
EU487217.1 Homo sapiens EWS/FLI fusion protein mRNA, complete cds P
AK096787.1 Homo sapiens cDNA FLJ39468 fis, clone PROST2012504, highly similar to RNA-BINDING PROTEIN EWS PA
AL833489.1 Homo sapiens mRNA; cDNA DKFZp686I2029 (from clone DKFZp686I2029) PA
X66899.1 H.sapiens EWS mRNA PA

EST sequences (10 of 2095) [Show all sequences]

AA968521.1 Clone IMAGE:1575011 kidney 3' read A
AA970893.1 Clone IMAGE:1572666 kidney 3' read PA
AA975296.1 Clone IMAGE:1588482 uncharacterized tissue 3' read A
AA988441.1 Clone IMAGE:1601891 lung 3' read P
AA993087.1 Clone IMAGE:1625044 embryonic tissue 3' read A
AA911782.1 Clone IMAGE:1519664 uncharacterized tissue 3' read PA
AI016994.1 Clone IMAGE:1635250 kidney 3' read PA
AA922583.1 Clone IMAGE:1551661 uncharacterized tissue 3' read PA
AI091290.1 Clone IMAGE:1651412 mixed 3' read P
CA976085.1 Clone IMAGE:6202495 nerve 5' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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