Morphine - Compound Summary (CID: 5288826)
The principal alkaloid in opium and the prototype opiate analgesic and narcotic. Morphine has widespread effects in the central nervous system and on smooth muscle.
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 Drug and Chemical Information: (Total:1)
Medication Information
Morphine is the most important alkaloid of opium and is a phenanthrene derivative. It is available as the sulfate salt, having the following structural formula: 7,8-Didehydro-4,5-epoxy-17-methyl-(5,6)-morphinan-3,6-diol sulfate (2:1)  AVINZA (morphine sulfate extended-release capsules) 30, 60, 90, and 120 mg contain both immediate release and extended release beads of morphine sulfate for once daily oral administration.Chemically, morphine sulfate is 7,8-didehydro-4,5 DepoDur (morphine sulfate extended-release liposome injection) is a sterile suspension of multivesicular liposomes using proprietary DepoFoam formulation technology containing morphine sulfate, intended for epidural Morphine is the most important alkaloid of opium and is a phenanthrene derivative. It is available as the sulfate salt, having the following structural formula:7,8-Didehydro-4,5-epoxy-17-methyl-(5,6)-morphinan-3,6-diol sulfate (2:1) Morphine Sulfate Extended-Release Tablets are supplied in tablet form for oral administration.Chemically, morphine sulfate is 7,8-didehydro-4,5-epoxy-17-methylmorphinan-3,6 -diol sulfate (2:1) (salt) pentahydrate and has the following Chemically, morphine sulfate is 7,8-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol sulfate (2:1) (salt) pentahydrate and has the following structural formula:(C17H19NO3)2H2SO4Molecular Weight: 668.77The mol Morphine is one of the naturally occurring phenanthrene alkaloids of opium derived from the opium poppy; it is classified pharmacologically as a narcotic analgesic. Morphine sulfate may be designated chemically as 7,8-didehydro-4,5a- Chemically, morphine sulfate is 7, 8-didehydro-4, 5-epoxy-17-methylmorphinan-3, 6-diol sulfate (2:1) (salt) pentahydrate. The molecular formula is (C17H19NO3)2H2SO45H2O; and the molecular weight is 758.83. The structural formula is as Chemically, morphine sulfate is 7,8-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol sulfate (2:1) (salt) pentahydrate and has the following structural formula:MS CONTIN (morphine sulfate controlled-release) Tablets are opiate analgesics Chemically, morphine sulfate is 7,8-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol sulfate (2:1) (salt) pentahydrate and has the following structural formula:Morphine sulfate extended-release tablets are opiate analgesics supplied in 100 Chemically, morphine sulfate is 7,8-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol sulfate (2:1) (salt) pentahydrate and has the following structural formula:Each morphine sulfate extended-release 30 mg unscored tablet, for oral Chemically, morphine sulfate is 7,8-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol sulfate (2:1) (salt) pentahydrate and has the following structural formula:Each Morphine Sulfate Extended-release Tablet for oral administration contains: Each tablet for oral administration contains:Morphine sulfate..........15 mg, 30 mg, 60 mg, or 100 mg in a tablet that provides for sustained release of the medication.Morphine sulfate occurs as white, feathery, silky crystals Morphine, the most important alkaloid of opium, is classified pharmacologically as a narcotic analgesic. Morphine Sulfate, USP (pentahydrate), is chemically designated 7, 8-didehydro-4, 5-epoxy-17-methylmorphinan-3, 6-diol sulfate (2:1) Preservative-free Morphine Sulfate Injection, USP is a sterile, nonpyrogenic, isobaric solution of morphine sulfate in water for injection.Each mL contains morphine sulfate, pentahydrate 0.5 mg or 1 mg (Warning: May be habit forming) and Safety and Toxicology
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 BioActivity Results:
Tested in BioAssays: All: 1 Active: 1
BioActivity Summary: This Compound with Similar Compounds
AID: 1195 Source: EPA DSSTox
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database
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 Properties Computed from Structure:
| Molecular Weight | 285.33766 [g/mol] | | Molecular Formula | C17H19NO3 | | XLogP | 0.8 | | H-Bond Donor | 2 | | H-Bond Acceptor | 4 | | Rotatable Bond Count | 0 | | Tautomer Count | 3 | | Exact Mass | 285.136493 | | MonoIsotopic Mass | 285.136493 | | Topological Polar Surface Area | 52.9 | | Heavy Atom Count | 21 | | Formal Charge | 0 | | Complexity | 494 | | Isotope Atom Count | 0 | | Defined Atom StereoCenter Count | 5 | | Undefined Atom StereoCenter Count | 0 | | Defined Bond StereoCenter Count | 0 | | Undefined Bond StereoCenter Count | 0 | | Covalently-Bonded Unit Count | 1 |
Descriptors Computed from Structure:
Canonical SMILES: CN1CCC23C4C1CC5=C2C(=C(C=C5)O)OC3C(C=C4)O
Isomeric SMILES: CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3[C@H](C=C4)O
InChI: InChI=1/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14
(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,
17-/m0/s1
Compound Information:
 Substance Information:
Substances:
All: 261 Links Same structure: 18 Links Mixture: 243 LinksCategory: [for same structure substances]
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| Compound ID | 5288826 |
| | Molecular Weight | 285.33766 [g/mol] |
| | Molecular Formula | C17H19NO3 |
| | XLogP | 0.8 |
| | H-Bond Donor | 2 |
| | H-Bond Acceptor | 4 |
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