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Biological Atomic Force Microscopy (AFM)
Four Multimodal AFM instrument
platforms at BIMI
![Four Multimodal AFM instrument platforms at BIMI](https://webarchive.library.unt.edu/eot2008/20090131052125im_/http://www.nibib.nih.gov/nibib/image/Research/Intramural/dbeps/images/JinAFMPagePhotosWebSize%20copy.png)
Photos by Jude Gustafson
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Contents
AFM Capabilities
Biomedical Instrumentation and Multiscale Imaging (BIMI) AFM Specialists
Recent Projects
AFM Capabilities
Combining high-resolution AFM under physiological conditions with sensitive force measurements
and mathematical modeling to gain greater understanding of complex biological systems.
Imaging
Atomic resolution: ~ 0.1 nm under physiological conditions, dynamic changes, temperature studies, etc.
Force Measurement
Biomolecular: ~ 1 pN to tissue level; ~1 m N force and force modulation
Commercial equipment
- Multimode PicoForce AFM
- TIRF AFM (Bioscope Z)
- Raman (LabRam) AFM (XE-120)
- Single Molecule Force Spectroscopy (SMFS) AFM (ForceRobot)
Technologies
- Multi-modality (Raman, TIRF, NSOM, etc.)
- Environmental Control
- Carbon Nanotube Tips
- Surface Modifications
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BIMI AFM Specialists
For more information, contact the BIMI staff:
Paul D. Smith, Ph.D. - Chief
Albert J. Jin, Ph.D. - Staff Scientist
Emilios K. Dimitriadis, Ph.D. - Staff Scientist
Minhua Zhou - NIH/NIST NRC Fellow
Svetlana Kotova - Visiting Fellow
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