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Summaries & Associations of Study Results
Summaries & Associations of Study Results
Home » Study Results & Research Projects » Summaries & Associations of Study Results » Levels from TR-529 2,2',4,4',5,5',-Hexachlorobiphenyl
CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
---|---|---|---|---|
TOXIC EQUIVALENCY FACTOR EVALUATION (PCB 153- 2,2'-4,4',5,5'- HEXACHLOROBIPHENYL) 35065-27-1 |
12/09/04 | Gavage FEMALE RATS ONLY: PCB-153 - 0, 10, 100, 300, 1000, OR 3000 UG/KG AND 3000 UG/KG (STOP-EXPOSURE); 50/DOSE | Battelle Columbus Laboratory | |
LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
FR: EQUIVOCAL EVIDENCE | LIVER: CHOLANGIOMA 0/53 0/54 0/53 0/53 2/53 0/51 2/50 | |||
NON-NEOPLASTIC LESIONS: | LIVER: HEPATOCYTE HYPERTROPHY; DIFFUSE FATTY CHANGE; BILE DUCT HYPERPLASIA; OVAL CELL HYPERPLASIA; PIGMENTATION | |||
THYROID GLAND: FOLLICULAR CELL HYPERTROPHY | ||||
OVARY: CHRONIC ACTIVE INFLAMMATION | ||||
OVIDUCT: CHRONIC ACTIVE INFLAMMATION | ||||
UTERUS: SUPPURATIVE INFLAMMATION; CHRONIC ACTIVE INFLAMMATION |
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