Concurrent Symposia Sessions

Wednesday, October 15, 2008
Natcher Conference Center
Symposia Session II
Balcony A

Immunotherapy vs. Immunosuppression	10:30 a.m. - 1:30 p.m.

Chair: Arya Biragyn, NIA

Immunotherapies for autoimmune diseases and cancer appear to pursue two opposing goals.  However, these two fields both concentrate on common processes, such as immunosuppression and immunotolerance.  On one hand, therapy of autoimmune diseases is aimed at restoration of tolerance.  On the other hand, the goal of cancer immunotherapy is to increase cancer immunogenicity and to circumvent immunosuppressive conditions and microenvironments.  Thus, the aim of this mini-symposium is to bring expert investigators from both fields together to initiate an exchange of ideas beneficial for the treatment of both diseases.  This session will also provide a rare opportunity to hear the most recent results and ideas on how to manipulate the immune system to augment or inhibit responses to self-antigens.

Program

Introduction
Arya Biragyn, NIA

Recent Developments in Human Cancer Immunotherapy
Steven A. Rosenberg, NCI

Apoptosis-linked Immunoregulation: Implications in Immunotherapy for Autoimmune Diseases and Cancer
Wanjun Chen, NIDCR

Cytokines Produced by NKT Cells and Autoimmune Disease
Rachel Caspi, NEI

Targeting Jak3
Kamran Choreschi, NIAMS

Combining Proteasome Inhibition with the Immunotherapy of Cancer
Tom Sayers, NCI

Tracking CD4 Treg Cells in Autoimmune Disease and Cancer
Xin Chen, NCI

Control of Breast Cancer Lung Metastasis via Chemokine Receptor CCR4 Targeting Strategies   
Arya Biragyn, NIA