Chief, George P. Chrousos, M.D.
Clinical Center, Building 10, Room 9D42
10 Center Drive, MSC 1583
Bethesda, MD 20892-1583
Phone: (301) 496-5800
Fax: (301) 402-0884
E-mail: chrousog@mail.nih.gov

The PREB performs biomedical research, provides training, and has clinical activities in two large areas, Pediatric Endocrinology Metabolism and Reproductive Endocrinology and Infertility. Its major focus is the physiology and pathophysiology of growth, development, metabolic, immune, and reproductive functions and the study of the major neurohormonal systems, the hypothalamic-pituitary-adrenal (HPA) and –gonadal (HPG) axes and the autonomic nervous system. Both developmental and static functions of these systems are studied in the in vivo, integrated, and the reduced, cellular, subcellular, and genomic levels. Studies of these systems are performed in normal human volunteers throughout the life span, in patients with endocrine disorders, and in appropriate animal models; the cellular and molecular actions of the key effector molecules of the HPA-HPG axes and autonomic system are studied in appropriate cell systems.

The PREB has under its auspices the Pediatric Endocrinology Training Program and Reproductive Endocrinology and Infertility Training Program both approved by the Accreditation Council for Graduate Medical Education (ACGME). The PREB participates in the Adult Inter-Institute Endocrinology and Metabolism Program run by NIDDK on behalf of the National Institutes of Health (link to site). Physician scientists from PREB admit patients to the Clinical Center for research directed by approved clinical protocols.