National Toxicology Program

CASRN: 842-07-9

Formula: C16-H12-N2-O

Synonyms/Common Names:

• 1-(PHENYLAZO)-2-NAPTHALENO) (9CI)
• YELLOW 14, C.I. SOLVENT

Known Uses:

MONOAZO DYE IN HYDROCARBON SOLVENTS, OILS, FATS, SHOE POLISH, GASOLINE, SOAP

Short-Term Toxicity

• 14-Day (Dosed-Feed)  (C53929) Completed 
  • NTIS No. PB83-126474  (Peer Review 02/18/1981)
    Citation: Carcinogenesis Bioassay of C.I. Solvent Yellow 14 (CAS No. 842-07-9) in F344/N Rats and B6C3F1 Mice (Feed Study)
  • Rats: F344/N; Mice: B6C3F1
• 13-Week (Dosed-Feed)  (C53929) Completed 
  • NTIS No. PB83-126474  (Peer Review 02/18/1981)
    Citation: Carcinogenesis Bioassay of C.I. Solvent Yellow 14 (CAS No. 842-07-9) in F344/N Rats and B6C3F1 Mice (Feed Study)
  • Rats: F344/N; Mice: B6C3F1
  • Dose: R: 0,250,4000, M: 0,500,4000 PPM/10 PER GROUP

Long-Term Carcinogenicity

• 2-Year (Dosed-Feed)  (C53929) Report Complete 
  • TR-226 (NTIS No. PB83-126474)  (Peer Review 02/18/1981)
    Carcinogenesis Bioassay of C.I. Solvent Yellow 14 (CAS No. 842-07-9) in F344/N Rats and B6C3F1 Mice (Feed Study)
  • Rats: F344/N; Mice: B6C3F1
  • Carcinogenesis Results
  • Male Rats Positive 
  • Female Rats Positive 
  • Male Mice Negative 
  • Female Mice Negative 
  • Dose: R: 0,250,500, M: 0,500,1000 PPM/50 PER GROUP

Genetic Toxicology

• Chromosome Aberrations  (114547) Completed 
  • Mice
  • Chromosome Aberation  Negative 
• In Vitro Cytogenetics (CA/SCE)  (247659) Completed 
  • Citation: Ivett, J.L., Brown, B.M., Rodgers, C., Anderson, B.E., Resnick, M.A., Zeiger, E. Chromosomal aberration and sister chromatid exchange tests in Chinese hamster ovary cells in Vitro IV: Results for l5 chemicals Environ. Molec. Mutagen. Vol. 14 (1989) 165-187
  • Chromosome Aberation Negative 
  • Sister Chromatid Exchange Positive 
• Drosophila  (700839) Completed 
  • Citation: Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. X. Results of 70 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 208-227
  • Reciprocal Translocation/Sex-Linked Recessive Lethal Negative 
• Mouse Lymphoma  (841852) Completed 
  • Citation: McGregor, D., Brown, A., Howgate, S., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay. IV: 27 coded chemicals. Environ. Molec. Mutagen. Vol. 17 (1991) 196-219
  •  Positive 
• Micronucleus  (666998) Completed 
  • Mice: B6C3F1
  • Male Equivocal 
• Salmonella  (318291) Completed 
  • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
  •  Positive 
• Salmonella  (916978) Completed 
  •  Positive 
• Sister Chromatid Exchanges  (114547) Completed 
  • Mice
  • Sister Chromatid  Positive