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Laboratory for the Assessment of Medical Imaging Systems (LAMIS)

	photo by Jude Gustafson Dr. Marios Gavrielides is one of five NIBIB fellows working at LAMIS.

Contents

• Overview of LAMIS
• Research Programs
• Research Facilities and Equipment
• Goals
• NIBIB/CDRH Fellows
• FDA CDRH Staff

Overview

The Laboratory for the Assessment of Medical Imaging Systems (LAMIS) is a collaborative effort between the U.S. Food and Drug Administration (FDA) Center for Devices and Radiological Health (CDRH) and NIBIB that was established in 2004 as part of the NIBIB Intramural Research Program. The NIBIB provides postdoctoral researchers and equipment, while CDRH provides lab space, computer infrastructure, and mentoring staff. Researchers' unifying goal is to make safe and effective medical imaging products available to patients as quickly as possible, and the Diagnostic Imaging Lab has already achieved international prominence in development and evaluation of assessment methodologies for medical imaging systems.

	photo by Jude Gustafson Dr. Kyle Myers serves as mentor for LAMIS projects.

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LAMIS Research Programs

• In Silico Imaging Program 
• Implications of Gender-based Differences in Cardiovascular Disease on Imaging for Treatment and Diagnosis
• Patient Safety and Imaging Performance of Three-dimensional X-ray Imaging Systems for Detection of Breast Cancer
• Disease Quantitation in Lung CT
• Image Evaluation Methodology Development

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LAMIS Research Facilities and Equipment

• High-performance computer cluster
• Multiple x-ray systems for 2-D, 3-D, and 4-D imaging
• CCD cameras and positioning equipment
• Film processor, microdensitometer, and digitizers
• Digital microscope
• State-of-the-art display evaluation lab
• US tissue characterization equipment
  • Lunar Achilles Plus clinical US bond densitometer
  • Laboratory US data acquisition system

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Lab Goals

• Develop evaluation methodology based on advanced statistical tools
• Provide advanced image evaluation methods to researchers and system developers
• Determine fundamental limitations imposed on imaging systems by physical, biological, chemical, and statistical laws
• Characterize and optimize medical imaging systems and components
• Build consensus through publications, collaboration,  standards and FDA guidance
• Facilitate the rapid deployment of improved imaging systems and components to the patient community

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NIBIB/CDRH Fellows

• Marios A. Gavrielides, Ph.D.
• Lisa M. Kinnard, Ph.D.
• Iacovos S. Kyprianou, Ph.D.
• Subok Park, Ph.D.
• Melanie Freed, M.S.

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FDA CDRH Staff

• Aldo Badano, Ph.D.
• Jonathan S. Boswell, Ph.D.
• David G. Brown, Ph.D.
• Weijie Chen, Ph.D.
• Brandon D. Gallas, Ph.D.
• Jacqueline Haynes
• Elizabeth Hsu, Ph.D. (NCI IOTF)
• Robert J. Jennings, Ph.D.
• Hongye Liang, Ph.D.
• Kyle J. Myers, Ph.D.
• Eugene O'Brien, M.S.
• Sophie O. Paquerault, Ph.D.
• Nicholas A. Petrick, Ph.D.
• Frank W. Samuelson, Ph.D.
• Robert F. Wagner, Ph.D.
• Keith A. Wear, Ph.D.
• Rongping Zeng, Ph.D.

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