Cancer Center Director: Russel E. Kaufman, M.D. 3601 Spruce Street Philadelphia PA 19104-4268 Tel: (215) 898-3926 Fax: (215) 573-2097 kaufman@wistar.org Visit Website

The Wistar Institute Cancer Center conducts leading-edge basic and translational cancer research. Areas of established scientific strength include cancer genetics, tumor biology, and immunology. Within the Cancer Center is the Albert R. Taxin Brain Tumor Research Center, dedicated to making progress against these difficult-to-treat cancers. The Wistar Institute Cancer Center is home to one of only three SPORE (Specialized Programs of Research Excellence) grants targeting skin cancers. Institute researchers are international leaders in the area of gene expression and regulation, with pronounced accomplishment in chromatin remodeling studies. Wistar investigators are elucidating the biogenesis of microRNAs, small non-coding RNA molecules responsible for targeted gene silencing in development and differentiation that also play a role in cancer. In the fast-changing field of systems biology, Wistar scientists are among those creating the new technologies to push forward genomics- and proteomics-based cancer investigations. Recent cancer research from Wistar scientists has appeared in Science, Nature, Cell, and many other high-impact publications, confirming the creative productivity of Wistar’s intimate, collaborative, and interdisciplinary scientific culture.