[GHD Membership Roster] [GHD Meeting Rosters]

The GHD Study Section will review applications involving the discovery, application and interpretation of genetic and genomic variation in human phenotype and disease.  Specific areas are:

• Discovery of genes and genetic variation for human health, disease, and disease susceptibility:  Complex and Mendelian diseases such as psychiatric, neurological, ophthalmological, auditory, endocrinological, cardiovascular, developmental, reproductive, oncological, autoimmune, urological, respiratory; use of sophisticated genetic and genomic methods to identify candidate genes, single nucleotide polymorphisms, haplotypes, and copy number variation.
• Gene discovery and functional analysis using animal and cellular (human and animal) models:  Development of explicit models of human genetic disease using vertebrate animals such as mice, rats, dogs, and non-human primates; use of models for studies of candidate genes and their functional analysis, pathogenetics, positional cloning, quantitative loci.
• Epigenetics and disease:  Abnormalities in imprinting or X inactivation that lead to disease; gene and environmental interactions, or maternal genotypes that lead to epigenetic changes and disease; variation in epigenetic marks, non-coding RNAs, and epigenome mapping.
• Cytogenetics and disease:  Chromosomal and genomic disorders, aneuploidy, translocations, mosaicism, chimerism, dosage effects.

Study sections with most closely related areas of similar science listed in rank order are:

Genomics, Computational Biology and Technology [GCAT] 
Gene Therapy and Inborn Errors [GTIE] 
Genetic Variation and Evolution [GVE] 
Behavioral Genetics and Epidemiology [BGES] 
Epidemiology of Cancer [EPIC] 
Cancer Genetics [CG] 
Molecular Neurogenetics [MNG]