Biophysical Chemistry: analysis of interaction of biological molecules (protein-protein, protein-nucleic acid, ligand-receptor, small molecule – protein, small molecule-nucleic acid); specificity, stoichiometry, thermodynamics and kinetics
Biochemistry: mechanism of enzyme action, inhibition and regulation of enzymatic activity, binding assay development, chromatography, analytical electrophoresis, chemical and target directed modification of biological molecules, drug design
Molecular Biology: expression and purification of proteins for structural and functional analysis, in vitro expression and purification of proteins containing synthetic amino acids at predetermined sites employing readthrough of nonsense codons with misacylated suppressor tRNAs, isolation and characterization of nucleic acids