Organization and Function of the Synapse Proteome: A Cognitive Machine

 


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Air date: Wednesday, March 09, 2005, 3:00:00 PM
Category: Wednesday Afternoon Lectures
Description: Molecular network approaches are well suited to studying the architecture and function of the synapse proteome. The synapse proteome comprises ~1000 proteins which are amenable to genomic, genetic and proteomic approaches. As a paradigm we have studied the NRC, a 185 protein subset of the synapse proteome. The NRC comprises the 2-3 MDa protein complexes of the N-methyl-D-aspartate (NMDA) subtype of glutamate receptor , Post Synaptic Density 95, signalling proteins and other proteins that reside in the postsynaptic terminal.

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The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
Author: Seth Grant, Ph.D., Wellcome Trust Sanger Institute
Runtime: 75 minutes
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CIT File ID: 12505
CIT Live ID: 3445
Permanent link: http://videocast.nih.gov/launch.asp?12505