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Overview of the Laboratory of Bioengineering and Physical Science (LBPS)

The Laboratory of Bioengineering and Physical Science specializes in the development and application of cutting-edge technologies, based upon engineering, mathematics, and the physical sciences, for the solution of problems in biology and medicine. It collaborates with intramural scientists and proposes and develops theoretical and experimental methods important to the long term needs of the NIH. Its unique expertise spans technologies ranging in scale from near-atomic resolution to intact organisms.

LBPS staff members are organized into six research groups that support the NIH Intramural Program.

• Drug Delivery and Kinetics: Pharmacokinetics, regional drug administration, spatially-distributed models, analysis of biochemical networks, fluid mechanics
• Biomedical Instrumentation and Multiscale Imaging: Conception, design, development, and evaluation of innovative scientific instruments and systems 
• Ultramicro Immunodiagnostics: Measurement and characterization of biological materials in ultramicro samples and single cells
• Dynamics of Macromolecular Assembly: Protein interactions, determination of assembly state, size and shape in solution, and relationship to function
• Supramolecular Structure and Function: Determination of the organization and composition of supramolecular assemblies and small organelles in a cellular context

LBPS Contact Information

Richard D. Leapman, Ph.D.
Chief, LBPS
Bldg. 13, Rm. 3N 17
Tel: (301) 496-2599
Fax: (301) 496-6608
E-mail: leapmanr@mail.nih.gov

Henry S. Eden, M.D., Ph.D.
Deputy Chief, LBPS
Bldg. 13, Rm. 3N 17
Tel: (301) 435-1953
Fax: (301) 496-6608
E-mail: hanke@mail.nih.gov