Inflammatory Kidney Disease : NIDDK

Inflammatory Kidney Disease

The Inflammatory Kidney Diseases Program focuses on the study of both normal and pathologic renal processes involving immune-mediated or inflammatory-mediated mechanisms. Major areas of interest include studying basic processes that induce kidney cell damage and propagate kidney inflammation in the setting of systemic diseases and primary renal disorders, including renal transplant rejection. These processes include the regulation of renal cell-signaling pathways, cell-surface determinant expression, cellular matrix protein expression, as well as examining the regulation of cytokine and growth factor expression in inflammatory renal disease. These studies also investigate the interaction of a number of immune cells, such as T and B cell lymphocytes, neutrophils, and macrophages, with renal-specific cell subsets. Various experimental approaches are implemented in evaluating the mechanisms underlying these processes, such as basic cell culture systems, molecular biologic techniques, animal models of disease (including transgenic or knock-out systems), and human clinical trials.

For more information, contact Dr. Catherine M. Meyers, DKUH, Inflammatory Kidney Disease Program Director.

Resources for Researchers

Clinical Research

Centers

  • O'Brien Kidney and Urology Research Centers - Overview & Map
  • Polycystic Kidney Disease Research & Translation Centers - Overview & Map
  • Research Centers of Excellence in Pediatric Nephrology - Overview & Map

Committees and Advisory Groups

Related Study Sections

NIDDK Staff

Funding Opportunities

Funding for Special Communities

Conferences

Related Reports

Related Organizations

See Also



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Page last updated: January 23, 2009

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