NCI-Frederick: Small Animal Imaging Program (SAIP)
Overview: The NCI-Frederick Small Animal Imaging
Program was established to provide NCI Investigators with a state-of-the-art In
Vivo imaging facility. The SAIP became operational in October
2006 in Building 553 with the installation of a 3.0 Tesla MRI unit.
Since then, we have added additional equipment including a Xenogen IVIS SPECTRUM
for bioluminescence and fluorescence imaging, a CRi Maestro for fluorescence
imaging, a VisualSonics Vevo 770 40Mhz Ultrasound unit for real time sonography,
and a Siemens Inveon MicroPET scanner. We anticipate the arrival of a Siemens
Inveon microSPECT/CT imaging platform which will dock to the microPET device
and a Fuji FLA-5100 autoradiography/fluorescence/chemiluminescence unit later
in 2007.
For more information on the available services, please view the following
pages:
If you have any questions concerning whether in vivo imaging is appropriate
in your research, please contact Peter Choyke (Molecular Imaging Program,
NCI) pchoyke@nih.gov.
How to Utilize the SAIP
In order to conduct imaging experiments in the SAIP-F you will need:
- A maximum of one page write-up of your proposal for consideration by
the SAIP steering committee which meets monthly (more frequently as needed). The
information provided will assist the SAIP Scientific Steering Committee
to determine the optimum imaging protocol. Submission is by a downloaded
form.
- The information provided by the NCI-investigator and the SAIP members
via the imaging service request form provides the pertinent information
for requesting an ACUC designated review.
- To Download the Imaging Service Request Form: Click Here.
Once your ASP is approved by ACUC (designated review) you will be able to
schedule imaging time on the appropriate device with Joseph Kalen, Director
of the SAIP, kalenj@mail.nih.gov. If
you will be scanning or even entering Building 553 you are required
to take the MR safety course. This is for your safety and the
safety of others who will also be in the vicinity of a high magnetic field. Contact
Lilia Ileva ileval@mail.nih.gov to
schedule a safety training session. Animals can be housed either
in your local facility at Frederick and transported through a pass-through
device in Building 553 OR they may be housed in Building 550 which is connected
to 553. All animals to be imaged will be transported in a plastic commercial
shipper container to SAIP (Bldg 553) in accordance with approved transportation
policies and procedures (LASP SOP 3.009). All scanning with SAIP imaging
devices must be performed under the supervision of SAIP staff.
Contact Information
NCI Administration
- Associate Project Officer: Peter L. Choyke, MD
SAIP Administration & Research Staff
- Director: Joseph D. Kalen, Ph.D. MSHA
- Senior Research Associate (MRI): Lilia Ileva, MS
- Research Associate (Animal technical support and Ultrasound): Lisa
Riffle
- Senior Research Associate (Nuclear):
- Research Associate (Optical):
Technical Support: NCI Molecular Imaging Program
- Pete Choyke, MD
- Marcelino Bernardo
NCI Scientific Steering Committee
- Peter L. Choyke, MD (CCR/MIP)
- Piotr Grodzinski, Ph.D. (OD-Nanotechnology)
- Kristin Komschlies, M.D. (OD-Frederick)
- James L. Tatum, M.D. (DCTD/CIP)
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