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Sponsored by: |
National Institute of Mental Health (NIMH) |
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Information provided by: | National Institutes of Health Clinical Center (CC) |
ClinicalTrials.gov Identifier: | NCT00001260 |
The purpose of this study is to collect and study the brain tissue of deceased individuals to learn more about the nervous system and mental disorders. Information gained from donated tissue may lead to better treatments and potential cures for nervous system and mental disorders.
This study will ask relatives of deceased individuals to donate the brains of their deceased relatives to allow further study of neurological and psychiatric disorders....
Condition |
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Bipolar Disorder Depression Anxiety Disorders Schizophrenia Tourette's Syndrome Brain Diseases |
Study Type: | Observational |
Official Title: | Brain Procurement for the Neuropathology Section, CBDB |
Estimated Enrollment: | 2000 |
Study Start Date: | May 1990 |
The knowledge of how affected tissue deviates from normal control tissue is an integral part of fully understanding a neurological or psychiatric disorder. The purpose of this protocol is to establish a coordinating program with the pathology departments of the Washington, D.C. and metropolitan area hospitals and local medical examiner's offices for the donation of brain tissue.
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Brain tissue is needed from individuals suffering from a variety of neuropsychiatric disorders, especially schizophrenia, but also anxiety disorders, suicide, bipolar disorder, depression, Tourette's Syndrome, drug addictions (PCP, cocaine, alcohol, heroin or the like) and any form of dementia. In addition, brains from normal individuals without a history of neuropsychiatric disease will be needed for controls.
Contact: Joel E. Kleinman, M.D. | (301) 402-7909 | kleinmaj@intra.nimh.nih.gov |
United States, District of Columbia | |
Office of the Chief Medical Examiner | Recruiting |
Washington, District of Columbia, United States, 20003 | |
United States, Maryland | |
National Institutes of Health Clinical Center, 9000 Rockville Pike | Recruiting |
Bethesda, Maryland, United States, 20892 | |
United States, Virginia | |
Office of the Chief Medical Examiner | Recruiting |
Fairfax, Virginia, United States, 22032 |
Study ID Numbers: | 900142, 90-M-0142 |
Study First Received: | November 3, 1999 |
Last Updated: | July 18, 2008 |
ClinicalTrials.gov Identifier: | NCT00001260 |
Health Authority: | United States: Federal Government |
Schizophrenia Neuropathology Neurochemistry Substance Abuse Bipolar Disorder Aging Normal Development Depression Anxiety Disorders |
Suicide Dementia Depression Bipolar Disorder Neuropsychiatric Disorders Suicide Tourette's Syndrome Normal Controls Schizophrenia |
Basal Ganglia Diseases Suicide Brain Diseases Neurodegenerative Diseases Tics Schizophrenia Affective Disorders, Psychotic Heredodegenerative Disorders, Nervous System Mental Disorders Movement Disorders Mental Disorders Diagnosed in Childhood Psychotic Disorders Dementia |
Schizophrenia and Disorders with Psychotic Features Depression Ganglion Cysts Bipolar Disorder Central Nervous System Diseases Tourette Syndrome Tic Disorders Depressive Disorder Behavioral Symptoms Anxiety Disorders Genetic Diseases, Inborn Mood Disorders Gilles de la Tourette's syndrome |
Pathologic Processes Disease Syndrome Nervous System Diseases |