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Model Detail

Mouse Model Information
Model Name	MBD4 null
Investigator	David Johnson
Status	available
Availability	n/a
Strain	n/a
Species of Origin	None selected
Mutation Type	Null
Manipulation Type	targeted
Conditional	N
Projected Use	Tool, cancer
Phenotype Summary	Mice that are homozygous for a null mutation are viable. Cells show increased C-T transitions and the mice show cancer predisposition
Genetic Information
Gene Name	methyl-CpG binding domain protein 4
Gene Symbol	MBD4
Reference Sequence	6754651
MGI Gene Record	MBD4 gene detail
LocusLink	17193
Disease	n/a
OMIM	n/a
Gene Models	n/a
Biopathways	n/a
Gene Ontology
Molecular Function	DNA binding
Biological Process	DNA methylation
Cellular Component	nucleus
Publications
Title	n/a

This page URL: http://tools.niehs.nih.gov/genotype/detail.cfm
NIEHS website: http://www.niehs.nih.gov/
Email the Web Manager at webmanager@niehs.nih.gov

Last Reviewed: 21 August 2007