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Model Detail
Mouse Model Information
Model Name
Exo 1 null
Investigator
Raju Kucherlapati
Status
available
Availability
n/a
Strain
n/a
Species of Origin
Mouse
Mutation Type
Null
Manipulation Type
targeted
Conditional
N
Projected Use
Tool, cancer
Phenotype Summary
Mice that are homozygous for the mutation are viable but sterile. The cells show decreased mismatch repair capability and the mice have a cancer predisposition
Genetic Information
Gene Name
exonuclease 1
Gene Symbol
EXO1
Reference Sequence
n/a
MGI Gene Record
n/a
LocusLink
n/a
Disease
n/a
OMIM
n/a
Gene Models
n/a
Biopathways
n/a
Gene Ontology
Molecular Function
Exonuclease
Biological Process
DNA repair
Cellular Component
nucleus
Publications
Title
n/a