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Model Detail

   
Mouse Model Information
Model Name Exo 1 null
Investigator Raju Kucherlapati
Status available
Availability n/a
Strain n/a
Species of Origin Mouse
Mutation Type Null
Manipulation Type targeted
Conditional N
Projected Use Tool, cancer
Phenotype Summary Mice that are homozygous for the mutation are viable but sterile. The cells show decreased mismatch repair capability and the mice have a cancer predisposition
Genetic Information
Gene Name exonuclease 1
Gene Symbol EXO1
Reference Sequence n/a
MGI Gene Record n/a
LocusLink n/a
Disease n/a
OMIM n/a
Gene Models n/a
Biopathways n/a
Gene Ontology
Molecular Function Exonuclease
Biological Process DNA repair
Cellular Component nucleus
Publications
Title n/a
   
USA.gov Department of Health & Human Services National Institutes of Health
This page URL: http://tools.niehs.nih.gov/genotype/detail.cfm
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Last Reviewed: 21 August 2007