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Model Detail

Mouse Model Information
Model Name	Brca1 cre Null
Investigator	David Johnson
Status	available
Availability	n/a
Strain	None selected
Species of Origin	Mouse
Mutation Type	loxP Sites
Manipulation Type	targeted
Conditional	Y
Projected Use	Tool, cancer
Phenotype Summary	n/a
Genetic Information
Gene Name	breast cancer 1, early onset
Gene Symbol	BRCA1
Reference Sequence	n/a
MGI Gene Record	Brca1 Gene details
LocusLink	12189
Disease	cancer
OMIM	113705
Gene Models	n/a
Biopathways	n/a
Gene Ontology
Molecular Function	DNA binding
Biological Process	DNA Repair
Cellular Component	Nucleus
Publications
Title	Berton TR, Matsumoto T, Page A, Conti CJ, Deng C-X,Jorcano JL, Johnson DG. Tumor formation in mice with conditional inactivation of Brca1 in epithelial tissues. Oncogene (2003) 22:5415-5426

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Last Reviewed: 21 August 2007