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Model Detail

Mouse Model Information
Model Name	Fen1 null
Investigator	Raju Kucherlapati
Status	available
Availability	MMHCC
Strain	n/a
Species of Origin	None selected
Mutation Type	Null
Manipulation Type	targeted
Conditional	N
Projected Use	Tool, cancer
Phenotype Summary	Mice that are homozygous are lethal. Heterozygous mice show mild phenotypes. When combined with Apc1638 shows an increased tumor incidence
Genetic Information
Gene Name	flap structure-specific endonuclease 1
Gene Symbol	FEN1
Reference Sequence	47132513
MGI Gene Record	Fen1 Gene Detail
LocusLink	14156
Disease	n/a
OMIM	600393
Gene Models	n/a
Biopathways	n/a
Gene Ontology
Molecular Function	endonuclease activity
Biological Process	DNA replication
Cellular Component	nucleus
Publications
Title	n/a

This page URL: http://tools.niehs.nih.gov/genotype/detail.cfm
NIEHS website: http://www.niehs.nih.gov/
Email the Web Manager at webmanager@niehs.nih.gov

Last Reviewed: 21 August 2007