Selective Bibliography of Dr. Eddy Arnold
Professor of Chemistry and Chemical Biology
Center for Advanced Biotechnology and Medicine
Rutgers, the State University of New Jersey

Thursday, November 20, 2008

1. Mukhopadhyay J, Das K, Ismail S, Koppstein D, Jang M, Hudson B, Sarafianos S, Tuske S, Patel J, Jansen R, Irschik H, Arnold E, Ebright RH
The RNA polymerase "switch region" is a target for inhibitors
CELL 135 (2):295-307 Oct 17 2008

2. Das K, Ma LC, Xiao R, Radvansky B, Aramini J, Zhao L, Marklund J, Kuo RL, Twu KY, Arnold E, Krug RM, Montelione GT
Structural basis for suppression of a host antiviral response by influenza A virus
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105 (35):13093-13098 Sep 2 2008

3. Bauman JD, Das K, Ho WC, Baweja M, Himmel DM, Clark AD, Jr., Oren DA, Boyer PL, Hughes SH, Shatkin AJ, Arnold E
Crystal engineering of HIV-1 reverse transcriptase for structure-based drug design
NUCLEIC ACIDS RESEARCH 36 (15):5083-5092 Sep 2008

4. Arnold E, Sarafianos SG
Molecular biology: an HIV secret uncovered
NATURE 453 (7192):169-170 May 8 2008

5. Knight JL, Zhou Z, Gallicchio E, Himmel DM, Friesner RA, Arnold E, Levy RM
Exploring structural variability in X-ray crystallographic models using protein local optimization by torsion-angle sampling
ACTA CRYSTALLOGRAPHICA SECTION D BIOLOGICAL CRYSTALLOGRAPHY 64 (Pt 4):383-396 Apr 2008

6. Das K, Bauman JD, Clark AD, Jr., Frenkel YV, Lewi PJ, Shatkin AJ, Hughes SH, Arnold E
High-resolution structures of HIV-1 reverse transcriptase/TMC278 complexes: strategic flexibility explains potency against resistance mutations
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105 (5):1466-1471 Feb 5 2008

7. Fang C, Bauman JD, Das K, Remorino A, Arnold E, Hochstrasser RM
Two-dimensional infrared spectra reveal relaxation of the nonnucleoside inhibitor TMC278 complexed with HIV-1 reverse transcriptase
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105 (5):1472-1477 Feb 5 2008

8. Kawamoto A, Kodama E, Sarafianos SG, Sakagami Y, Kohgo S, Kitano K, Ashida N, Iwai Y, Hayakawa H, Nakata H, Mitsuya H, Arnold E, Matsuoka M
2'-deoxy-4'-C-ethynyl-2-halo-adenosines active against drug-resistant human immunodeficiency virus type 1 variants
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 40 (11):2410-2420 2008

9. Han Q, Sarafianos SG, Arnold E, Parniak MA, Gaffney BL, Jones RA
Synthesis of AZTpSpCX2ppSA and AZTpSpCX2ppSAZT: hydrolysis-resistant potential inhibitors of the AZT excision reaction of HIV-1 RT
ORGANIC LETTERS 9 (25):5243-5246 Dec 6 2007

10. Morningstar ML, Roth T, Farnsworth DW, Smith MK, Watson K, Buckheit RW, Jr., Das K, Zhang W, Arnold E, Julias JG, Hughes SH, Michejda CJ
Synthesis, biological activity, and crystal structure of potent nonnucleoside inhibitors of HIV-1 reverse transcriptase that retain activity against mutant forms of the enzyme
JOURNAL OF MEDICINAL CHEMISTRY 50 (17):4003-4015 Aug 23 2007

Created 11/10/08