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Last Modified: 10/24/2008


1.		Phase II/III Randomized Comparison of Consolidation with Intensive Chemotherapy Using CDDP/VP-16/DOX/IFF vs Myeloablative Chemoradiotherapy and Autologous Marrow Rescue and of Continuation Therapy with Isotretinoin vs No Further Therapy in High-Risk Neuroblastoma

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III, Phase II				Treatment				Closed				0 to 18				NCI				CCG-3891

Last Modified: 2/1/1996


2.		Phase III Randomized Study of IFN-A with vs without 13-CRA in Patients with Metastatic Renal Cell Carcinoma (Summary Last Modified 02/96)

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Treatment				Completed				any age				NCI				MSKCC-94004 E-2894, NCI-T93-0198D, T93-0198

Last Modified: 5/8/2007 First Published: 5/1/1996


3.		Phase III Randomized Study of Interferon alfa With Versus Without Isotretinoin in Patients With Metastatic Renal Cell Cancer (Summary Last Modified 04/2001)

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Treatment				Closed				18 to 75								EORTC-30951 NCT00002737

Last Modified: 5/21/2007 First Published: 10/1/1998


4.		Phase III Randomized Study of Procarbazine With or Without Isotretinoin in Patients with Recurrent Primary Malignant Gliomas (Summary Last Modified 04/2000)

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Treatment				Closed				16 and over				NCI				MDA-DM-97050 NCI-T97-0078, NCT00003564, T97-0078

Last Modified: 5/21/2007 First Published: 11/1/1998


5.		Randomized Chemoprevention Study of Alpha-Tocopheral (Vitamin E) in Former and Current Smokers Receiving Isotretinoin (Summary Last Modified 04/2000)

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Prevention				Closed				18 and over				NCI				MDA-DM-97078 NCI-P98-0132, NCT00003599

Last Modified: 10/3/2007 First Published: 1/1/2000


6.		Phase III Randomized Study of Purged Versus Unpurged Peripheral Blood Stem Cell Transplantation After Dose-Intensive Induction Chemotherapy in Patients With Newly Diagnosed High Risk Neuroblastoma or Ganglioneuroblastoma

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Treatment				Completed				30 and under				NCI				COG-A3973 CCG-A3973, POG-A3973, CCG-39703, FHCRC-1631.00, NCT00004188, A3973

Last Modified: 1/14/2009 First Published: 11/1/2001


7.		Phase III Randomized Study of Adjuvant Isotretinoin With or Without Monoclonal Antibody Ch14.18, Interleukin-2, and Sargramostim (GM-CSF) in Patients With Neuroblastoma Who Have Completed Myeloablative Therapy and Autologous Stem Cell Transplantation

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Treatment				Temporarily closed				30 and under at diagnosis				NCI				COG-ANBL0032 ANBL0032, COG-P9842, NCT00026312


8.		Phase III Randomized Trial of Low-Dose ARA-C vs cis-Retinoic Acid in Preleukemia, ANLL, and CML

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Treatment				Closed				over 18								UCCRC-3723 ICC-82L4, NCI-V83-0135

Last Modified: 11/1/1987


9.		Phase III Prospective Double-Blind Randomized Study of Adjuvant Therapy with 13-cis Retinoic Acid vs Placebo in Adult Patients with Stage I/II/III/IV Squamous Cell Carcinoma of the Head and Neck (Summary Last Modified 11/87)

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Treatment				Closed				18 to 80								MDA-DM-8489 NCI-V85-0151

Last Modified: 8/1/1988


10.		Phase III Randomized Evaluation of Isotretinoin for the Prevention of Basal Cell Carcinoma in a High-Risk Population (Summary Last Modified 08/88)

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Prevention				Closed				40 to 75								DCPC-CPSB-10305

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