Agent Name |
N-Nitrosodi-n-propylamine |
Alternative Name |
NDPA |
CAS Number |
621-64-7 |
Formula |
C6-H14-N2-O |
Major Category |
Nitrogen Compounds |
Synonyms |
1-Propanamine, N-nitroso-N-propyl-; Di-n-propylnitrosamine; Di-n-propylnitrosoamine; Dipropylamine, N-nitroso-; Dipropylnitrosamine; N,N-Di-n-propylnitrosamine; N,N-Dipropylnitrosamine; N-Nitroso-N-propyl-1-propanamine; N-Nitrosodi-n-propylamine; N-Nitrosodipropylamine; Nitrosodipropylamine; Propanamine, N-nitroso-N-propyl-; Propylamine, N-nitroso-N-di-; [ChemIDplus] UN3077 |
Category |
Nitrosamines |
Description |
Yellow liquid; [HSDB] |
Sources/Uses |
Not produced in the United States; used primarily for research; [HSDB] "Small amounts of N-nitrosodi-n-propylamine are produced as a side reaction during some manufacturing processes, as a contaminant in some commonly available weed killers (dinitroaniline-based), and during the manufacture of some rubber products. When exposed to sunlight, N-nitrosodi-n-propylamine usually does not last for more than a day." [ATSDR ToxProfiles] |
Comments |
In animal experiments, N-nitrosodi-n-propylamine causes hepatic injury after acute exposure and cancer of the liver after chronic exposure. [ATSDR ToxProfiles] |
Exposure Assessment |
Skin Designation (ACGIH) |
Not evaluated |
Vapor Pressure |
0.08 mm Hg |
Explanatory Notes |
Carcinogen--No TLV; |
Reference Link |
ATSDR ToxFAQs - N-nitrosodi-n-propylamine |
Adverse Effects |
Hepatotoxin |
Hepatotoxin, Secondary |
IARC Carcinogen |
Possible Carcinogen |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: N-NITROSODI-N-PROPYLAMINE
|
|
|