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samarium Sm 153 lexidronam pentasodium
The pentasodium salt of samarium Sm 135 lexidronam, a therapeutic agent consisting of a medium energy beta- and gamma-emitting radioisotope, samarium Sm 135, and a teraphosphonate chelator, ethylenediaminetetramethylene phosphonic acid (EDTMP). The chelator moiety of samarium Sm 153 lexidronam associates with hydroxyapatite crystals concentrated in areas of bone turnover, thereby selectively delivering samarium Sm 153-mediated cytotoxic radiation to osteoblastic bone metastases. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | Samarium-153 EDTMP
Samarium-153 Ethylenediaminetetramethylenephosphonate
Samarium-153 Ethylenediaminetetramethylenephosphonic Acid
Sm-153 EDTMP | | | | US brand name: | | Quadramet | | | | Abbreviation: | | 153Sm-EDTMP | | |
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