| Disease/Syndrome |
Glanders |
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| Category |
Infection, Occupational |
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| Acute/Chronic |
Acute-Severe |
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| Synonyms |
Burkholderia mallei infection |
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| Biomedical References |
Search PubMed |
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| Comments |
FINDINGS: Localized skin infections after direct inoculation consist of ulcerating nodules with lymphangitis and lymphadenopathy. In the pulmonary form, patients have fever and pleurisy. The chest x-ray may show diffuse infiltrates, nodular densities, or lobar consolidation. The septicemic form may follow untreated lymph node infections to seed abscesses of the skin, liver, spleen, and lungs. [ID, p. 1463-4] The disease occurs in both acute and chronic forms. Findings include pustules, suppurating lymph nodes, hilar adenopathy, liver and spleen abscesses, and septicemia. [PPID, p. 2630] EPIDEMIOLOGY: This highly communicable disease of horses, mules, and donkeys rarely infects humans. Occupational infections occur in workers exposed to infected animals or laboratory cultures. [CCDM, p. 356] Humans become infected after contact with respiratory secretions and wound discharges from infected animals. Person-to-person transmission occurs. Only one case has been reported in the USA since 1944, and this was a worker in a biodefense laboratory. [ID, p. 1462] |
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| Latency/Incubation |
10 days to 2 weeks |
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| Diagnostic |
Culture; Serology; |
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| ICD-9 Code |
024 |
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| Effective Antimicrobics |
Yes |
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| Scope |
Asia, eastern Mediterranean countries; [CCDM, p. 356] Asia, Africa, and South America; [ID, p. 1463] |
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| Reference Link |
CDC - Glanders |
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| Related Information in Haz-Map |
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| Symptoms/Findings |
Symptoms/Findings associated with this disease:
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| Job Tasks |
High risk job tasks associated with this disease:
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