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navigation links             | ... | Full PubMed List of Publications by F. Maldarelli
Morse, C., and Maldarelli, F. (2009) HIV infection. In Strober, W., and Gottesman, S. (eds.), Immunology, Clinical Case Studies and Disease Pathophysiology, John Wiley & Sons, in press. Kearney,
M., Maldarelli, F., Shao, W., Margolick, J.B., Daar, E.S., Mellors, J.W.,
Rao, V., Coffin, J.M., and Palmer, S. (2009) HIV-1 population genetics
and adaptation in newly infected individuals. J. Virol. , in press (Dec
30 Epub ahead of print). Robertson,
S.M., Maldarelli, F., Natarajan, V., Formentini, E., Alfaro, R.M., and
Penzak, S.R. (2009) Efavirenz induces CYP2B6-mediated hydroxylation
of bupropion in healthy subjects. J. Acquir. Immune Defic. Syndr., in press
(Nov 4 Epub ahead of print). Porter, B.O., Anthony, K.B., Shen, J., Hahn, B., Keh, C.E., Maldarelli, F., Blackwelder, W.C., Lane, H.C., Kovacs, J.A., Davey, R.T., and Sereti, I. (2009) Inferiority of IL-2 alone versus IL-2 with HAART in maintaining CD4 T cell counts during HAART interruption: A randomized controlled trial. AIDS 23: 203-212. [Abstract] [Full-text PDF article - 252 K] Migueles,
S.A., Osborne, C.M., Royce, C., Compton, A.A., Joshi, R.P., Weeks, K.A., Rood,
J.E., Berkley, A.M., Sacha ,J.B., Cogliano-Shutta, N.A., Lloyd, M., Roby, G.,
Kwan, R., McLaughlin, M., Stallings, S., Rehm, C., O'Shea, M.A., Mican, J., Packard,
B.Z., Komoriya, A., Palmer, S., Wiegand, A.P., Maldarelli, F., Coffin,
J.M., Mellors, J.W., Hallahan, C.W., Follman, D.A., and Connors, M. (2008)
Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination
associated with immune control. Immunity 29: 1009-1021. Ramanathan, R., Pau, A.K., Busse, K.H., Zemskova, M., Nieman, L., Kwan, R., Hammer, J.H., Mican, J.M., and Maldarelli, F. (2008) Iatrogenic Cushing syndrome after epidural triamcinolone injections in an HIV type 1-infected patient receiving therapy with ritonavir-lopinavir. Clin. Infect. Dis. 47: e97-99. [Abstract] [Full-text PDF article - 109 K] Kutty,
G., Maldarelli, F., Achaz, G., and Kovacs, J.A. (2008) Variation
in the major surface glycoprotein genes in Pneumocystis jirovecii.
J. Infect. Dis. 198: 741-749. Palmer, S., Maldarelli, F., Wiegand, A., Bernstein, B., Hanna, G.J., Brun, S.C., Kempf, D.J., Mellors, J.W., Coffin, J.M., and King, M.S. (2008) Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy. Proc. Natl. Acad. Sci. USA 105: 3879-3884. [Abstract] [Full-text PDF article]
Kearney,
M., Palmer, S., Maldarelli, F., Shao, W., Polis, M.A., Mican, J., Rock-Kress,
D., Margolick, J.B., Coffin, J.M., and Mellors, J.W. (2008) Frequent
polymorphism at drug resistance sites in HIV-1 protease and reverse transcriptase.
AIDS 22: 497-501. Ambrose,
Z., Palmer, S., Boltz, V.F., Kearney, M., Larsen, K., Polacino, P., Flanary, L.,
Oswald, K., Piatak, M., Jr., Smedley, J., Shao, W., Bischofberger, N., Maldarelli,
F., Kimata, J.T., Mellors, J.W., Hu, S.-L., Coffin, J.M., Lifson, J.D., and
KewalRamani, V.N. (2007) Suppression of viremia and evolution of human
immunodeficiency virus type 1 drug resistance in a macaque model for antiretroviral
therapy. J. Virol. 81: 12145-12155. Maldarelli,
F., Palmer, S., King, M.S., Wiegand, A., Polis, M.A., Mican, J., Kovacs, J.A.,
Davey, R.T., Rock-Kress, D., Dewar, R., Liu, S., Metcalf, J.A., Rehm, C., Brun,
S.C., Hanna, G.J., Kempf, D.J., Coffin, J.M., and Mellors, J.W. (2007)
ART suppresses plasma HIV- 1 RNA to a stable set point predicted by pretherapy
viremia. PLoS Pathog. 3: e46. Morse, C., and Maldarelli, F. (2007) Enfuvirtide antiviral activity despite rebound viremia and resistance mutations: Fitness tampering or a case of persistent braking on entering? (Editorial Commentary). J. Infect. Dis. 195:318-321. [PubMed citation] [Full-text PDF article] Nikolenko, G.N., Delviks-Frankenberry, K.A., Palmer, S., Maldarelli, F., Fivash, M.J., Jr., Coffin, J.M., and Pathak, V.K. (2007) Mutations in the connection domain of HIV-1 reverse transcriptase increase 3'-azido-3'-deoxythymidine resistance. Proc. Natl. Acad. Sci. USA 104: 317-322. [Abstract] [Full-text PDF article] Gafni,
R.I., Hazra, R., Reynolds, J.C., Maldarelli, F., Tullio, A.N., DeCarlo,
E., Worrell, C.J., Flaherty, J., Yale, K., Kearney, B.P., and Zeichner, S.L.
(2006) Tenofovir disoproxil fumarate and an optimized background regimen
of antiretroviral agents as salvage therapy: Impact on bone mineral density in
HIV-infected children. Pediatrics 118: 711-718. Bashirova, A.A., Bleiber, G., Qi, Y., Hutcheson, H., Yamashita, T., Johnson, R.C., Cheng, J., Alter, G., Goedert, J.J., Buchbinder, S., Hoots, K., Vlahov, D., May, M., Maldarelli, F., Jacobson, L., O'Brien, S.J., Telenti, A., and Carrington, M. (2006) Consistent effects of TSG101 genetic variability on multiple outcomes of exposure to human immunodeficiency virus type 1. J. Virol. 80: 6757-6763. [Abstract] [Full-text PDF article] Palmer, S., Boltz, V., Martinson, N., Maldarelli, F., Gray, G., McIntyre, J., Mellors, J., Morris, L., and Coffin, J. (2006) Persistence of nevirapine-resistant HIV-1 in women after single-dose nevirapine therapy for prevention of maternal-to-fetal HIV-1 transmission. Proc. Natl. Acad. Sci. USA 103: 7094-7099. [Abstract] [Full-text PDF article] Palmer,
S., Boltz, V., Maldarelli, F., Kearney, M., Halvas, E.K., Rock, D., Falloon,
J., Davey, R.T., Jr., Dewar, R.L., Metcalf, J.A., Mellors, J.W., and Coffin, J.M.
(2006) Selection and persistence of non-nucleoside reverse transcriptase
inhibitor-resistant HIV-1 in patients starting and stopping non-nucleoside therapy.
AIDS 20: 701-710. Hazra,
R., Gafni, R.I., Maldarelli, F., Balis, F.M., Tullio, A.N., DeCarlo, E.,
Worrell, C.J., Steinberg, S.M., Flaherty, J., Yale, K., Kearney, B.P., and Zeichner,
S.L. (2005) Tenofovir disoproxil fumarate and an optimized background
regimen of antiretroviral agents as salvage therapy for pediatric HIV infection.
Pediatrics 116: e846-e854. Maldarelli, F. (2005) HIV drug resistance. In Zeichner, S.L., and Read, J.S., eds., Textbook of Pediatric HIV Care, Cambridge University Press, New York, pp. 334-354. Sklar,
P.A., Masur, H., Grubb, J.R., Voell, J., Witek, J., Ono, A., Freed, E.O., and
Maldarelli, F. (2005) Pravastin does not have a consistent
antiviral effect in chronically HIV-infected individuals on antiretroviral therapy.
AIDS 19: 1109-1111. Chen, J., Dang, Q., Unutmaz, D., Pathak, V.K., Maldarelli, F., Powell, D., and Hu, W.-S. (2005) Mechanisms of nonrandom human immunodeficiency virus type 1 infection and double infection: Preference in virus entry is important but is not the sole factor. J. Virol. 79: 4140-4149. [Abstract] [Full-text PDF article] Nikolenko, G.N., Palmer, S., Maldarelli, F., Mellors, J.W., Coffin, J.M., and Pathak, V.K. (2005) Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: Balance between RNase H activity and nucleotide excision. Proc. Natl. Acad. Sci. USA 102: 2093-2098. [Abstract] [Full-text PDF article] Palmer, S., Kearney, M., Maldarelli, F., Halvas, E.K., Bixby, C.J., Bazmi, H., Rock, D., Falloon, J., Davey, R.T., Jr., Dewar, R.L., Metcalf, J.A., Hammer, S., Mellors, J.W., and Coffin, J.M. (2005) Multiple, linked human immunodeficiency virus type 1 drug resistance mutations in treatment-experienced patients are missed by standard genotype analysis. J. Clin. Microbiol. 43: 406-413. [Abstract] [Full-text PDF article] Maldarelli, F. (2005) Detection of human immunodeficiency virus infection. In Mandell, G.L., Bennett, J.E., and Dolin, R., eds., Principles and Practice of Infectious Diseases, 6th edition, Vol. 1. Achaz, G., Palmer, S., Kearney, M., Maldarelli, F., Mellors, J.W., Coffin, J.M., and Wakeley, J. (2004) A robust measure of HIV-1 population turnover within chronically infected individuals. Mol. Biol. Evol. 21: 1902-1912. [Abstract] [Full-text PDF article] Dybul, M., Nies-Kraske, E., Dewar, R., Maldarelli, F., Hallahan, C.W., Daucher, M., Piscitelli, S.C., Ehler, L., Weigand, A., Palmer, S., Metcalf, J.A., Davey, R.T., Rock Kress, D.M., Powers, A., Beck, I., Frenkel, L., Baseler, M., Coffin, J., and Fauci, A.S. (2004) A proof-of-concept study of short-cycle intermittent antiretroviral therapy with a once-daily regimen of didanosine, lamivudine, and efavirenz for the treatment of chronic HIV infection. J. Infect. Dis. 189: 1974-1982. [Abstract] [Full-text PDF article] Kottilil, S., Jagannatha, S., Lu, A., Liu, S., McLaughlin, M., Metcalf, J.A., Dewar, R., Campbell, C., Koratich, C., Maldarelli, F., Masur, H., and Polis, M.A. (2004) Changes in hepatitis C viral response after initiation of highly active antiretroviral therapy and control of HIV viremia in chronically co-infected individuals. HIV Clin. Trials 5: 25-32. [Abstract] Dang,
Q., Chen, J., Unutmaz, D., Coffin, J.M., Pathak, V.K., Powell, D., KewalRamani,
V.N., Maldarelli, F., and Hu, W.-S. (2004) Nonrandom HIV-1
infection and double infection via direct and cell-mediated pathways. Proc.
Natl. Acad. Sci. USA 101: 632-637. Palmer,
S., Wiegand, A.P., Maldarelli, F., Bazmi, H., Mican, J.M., Polis, M., Dewar,
R.L., Planta, A., Liu, S., Metcalf, J.A., Mellors, J.W., and Coffin, J.M.
(2003) New real-time reverse transcriptase-initiated PCR assay with single-copy
sensitivity for human immunodeficiency virus type 1 RNA in plasma. J. Clin.
Microbiol. 41: 4531-4536. Kottilil,
S., Chun, T.W., Moir, S., Liu, S., McLaughlin, M., Hallahan, C.W., Maldarelli,
F., Corey, L., and Fauci, A.S. (2003) Innate immunity in human
immunodeficiency virus infection: Effect of viremia on natural killer cell
function. J. Infect. Dis. 187: 1038-1045. Maldarelli, F. (2003) HIV-1 fitness and replication capacity: What are they and can they help in patient management? Curr. Infect. Dis. Rep. 5: 77-84. [Abstract] Maldarelli, F. (2003) HIV drug resistance. In Zeichner, S., and Read, J., eds., Handbook of Pediatric HIV Care, Cambridge University Press. Maldarelli, F. (2003) HIV drug resistance testing. In Zeichner, S., and Read, J., eds., Manual of Pediatric HIV Care, Cambridge University Press. Palmer, S., Kearney, M., Maldarelli, F., Kottilil, S., Lucey, D., Metcalf, J., Rock, D., VanHoutte, M., Michels, L., Hertogs, K., Mellors, J., and Coffin, J. (2002) Genetics of HIV-1 populations in acute and chronic infection. Antiviral Ther. 7: S57. Maldarelli,
F. (2001) Meeting report: First HIV DRP Symposium 'Understanding Antiviral
Drug Resistance', Chantilly, Virginia, USA, December 3-6, 2000. Int. Antiviral
News 9: 36-39. Favaro, J.P., Maldarelli, F., Arrigo, S.J., and Schmidt, M.G. (1999) Effect of Rev on the cytoplasmic localization of intron-containing human immunodeficiency virus type 1 RNA. Virology 255: 237-249. [Abstract] [Full-text PDF article] Neuveut,
C., Low, K.G., Maldarelli, F., Schmitt, I., Majone, F., Grassmann, R.,
and Jeang, K.T. (1998) Human T-cell leukemia virus type 1 Tax and cell cycle progression:
Role of cyclin D-cdk and p110Rb. Mol. Cell. Biol. 18: 3620-3632. Maldarelli, F., Xiang, C., Chamoun, G., and Zeichner, S.L. (1998) The expression of the essential nuclear splicing factor SC35 is altered by human immunodeficiency virus infection. Virus Res. 53: 39-51. [Abstract] Smith, S.M., Maldarelli, F., and Jeang, K.T. (1997) Efficient expression by an alphavirus replicon of a functional ribozyme targeted to human immunodeficiency virus type 1. J. Virol. 71: 9713-9721. [Abstract] [Full-text PDF article] Hori, K., Hatfield, D., Maldarelli, F., Lee, B.J., and Clouse, K.A. (1997) Selenium supplementation suppresses tumor necrosis factor alpha-induced human immunodeficiency virus type 1 replication in vitro. AIDS Res. Hum. Retroviruses 13: 1325-1332. [Abstract] Shibata, R., Maldarelli, F., Siemon, C., Matano, T., Parta, M., Miller, G., Fredrickson, T., and Martin, M.A. (1997) Infection and pathogenicity of chimeric simian-human immunodeficiency viruses in macaques: Determinants of high virus loads and CD4 cell killing. J. Infect. Dis. 176: 362-373. [Abstract] Freed, E.O.,
Englund, G., Maldarelli, F., and Martin, M.A. (1997) Phosphorylation of
residue 131 of HIV-1 matrix is not required for macrophage infection. Cell 88:
171-173. Fujita,
K., Maldarelli, F., and Silver, J. (1996) Bimodal down-regulation of CD4
in cells expressing human immunodeficiency virus type 1 Vpu and Env. J. Gen. Virol.
77: 2393-2401. Berthold,
E., and Maldarelli, F. (1996) cis-Acting elements in human immunodeficiency
virus type 1 RNAs direct viral transcripts to distinct intranuclear locations. J. Virol. 70: 4667-4682. Maldarelli, F., Sato, H., Berthold, E., Orenstein, J., and Martin, M.A. (1995) Rapid induction of apoptosis by cell-to-cell transmission of human immunodeficiency virus type 1. J. Virol. 69: 6457-6465. [Abstract] [Full-text PDF article] *
Reprinted with permission from International
Medical Press. Last modified: 13 January 2009 | ... |
