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Odds of Beating Depression Diminish as Additional Treatment Strategies are Needed
November 1, 2006 • Science Update
An overall assessment of the nation's largest real-world study of treatment-resistant depression suggests that a patient with persistent depression can get well after trying several treatment strategies, but his or her odds of beating the depression diminish as additional treatment strategies are needed.
Preschoolers with ADHD Improve with Low Doses of Medication
October 16, 2006 • Press Release
The first long-term, large-scale study designed to determine the safety and effectiveness of treating preschoolers who have attention deficit/hyperactivity disorder (ADHD) with methylphenidate (Ritalin) has found that overall, low doses of this medication are effective and safe.
Antipsychotic Medications Used to Treat Alzheimer’s Patients Found Lacking
October 11, 2006 • Press Release
Commonly prescribed antipsychotic medications used to treat Alzheimer’s patients with delusions, aggression, hallucinations, and other similar symptoms can benefit some patients, but they appear to be no more effective than a placebo when adverse side effects are considered, according to the first phase of a large-scale clinical trial funded by NIMH.
NIMH Researchers Discover Medication’s Antidepressant Potential
October 2, 2006 • Science Update
A commonly used sedative and motion-sickness treatment shows promise as a fast-acting antidepressant, according to a study conducted by researchers at NIMH.
New Schizophrenia Trial: Does Method of Administering Medication Make a Difference?
September 5, 2006 • Science Update
A new clinical trial is testing whether an injection of a long-lasting antipsychotic medication every two weeks results in better adherence to treatment and better outcomes among people with schizophrenia than do oral medications taken daily.
Subsequent Treatment Strategies for Persistent Depression Yield Modest Results
September 1, 2006 • Science Update
Patients with treatment-resistant depression had a modest chance of becoming symptom-free when they tried different treatment strategies after two or three failed treatments, according to results from the nation's largest real-world study of depression.
Experimental Medication Kicks Depression in Hours Instead of Weeks
August 7, 2006 • Press Release
People with treatment—resistant depression experienced symptom relief in as little as two hours with a single intravenous dose of ketamine, a medication usually used in higher doses as an anesthetic in humans and animals, in a preliminary study.
Switching to a Third Antidepressant Medication May Prove Helpful to Some with Treatment-Resistant Depression
July 1, 2006 • Science Update
The next wave of results from the nation's largest real-world study of treatment-resistant depressionshows that patients had a moderate chance of becoming symptom-free when they switched to a third antidepressant medication, following two previously unsuccessful medication attempts.
Antipsychotic Prescriptions Rise Sharply for Children and Adolescents
June 19, 2006 • Science Update
The number of antipsychotic medication prescriptions for children and adolescents increased six-fold from 1993 to 2002, according to a study of visits made by people 20 years old and younger to doctors' offices.
Antidepressant Does Not Reduce Risk Of Relapse Among Patients With Anorexia Nervosa
June 14, 2006 • Science Update
An NIMH-funded study has concluded that the antidepressant medication fluoxetine (Prozac) is no more effective than placebo in preventing relapse among patients with anorexia nervosa who had achieved a healthy weight during inpatient or day-program treatment.
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