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Depression Rates Are Lower in Children Whose Mothers Are Successfully Treated
May 9, 2006 • Science Update
When women treated for depression become symptom-free, their children are less likely to be diagnosed with depression, according to a study published in the March 22/29 issue of the Journal of the American Medical Association.
Studies Offer New Information About Treatment Choices for Schizophrenia — Phase 2 Results
April 1, 2006 • Science Update
A national clinical trial comparing clozapine with other new-generation antipsychotic medications for the treatment of chronic schizophrenia has shown that people who switched to clozapine from their first medication because it failed to manage symptoms adequately were twice as likely to continue treatment as patients who switched to other antipsychotic medications.
New Strategies Help Depressed Patients Become Symptom-Free
March 23, 2006 • Press Release
Results of the nation’s largest depression study show that one in three depressed patients who previously did not achieve remission using an antidepressant became symptom-free with the help of an additional medication and one in four achieved remission after switching to a different antidepressant.
Maintenance Treatment Prevents Recurrence in Older Adults with Single-Episode Depression
March 16, 2006 • Press Release
People age 70 and older who continued taking the antidepressant that helped them to initially recover from their first episode of depression were 60 percent less likely to experience a new episode of depression over a two-year study period than those who stopped taking the medication, according to a study funded by the National Institute of Mental Health (NIMH), part of the National Institutes of Health.
Gene Influences Antidepressant Response
March 15, 2006 • Press Release
Whether depressed patients will respond to an antidepressant depends, in part, on which version of a gene they inherit, a study led by scientists at NIH has discovered. Having two copies of one version of a gene that codes for a component of the brain’s mood―regulating system increased the odds of a favorable response to an antidepressant by up to 18 percent, compared to having two copies of the other, more common version.
Lithium Blocks Enzyme To Help Cells’ Clocks Keep On Tickin’
February 17, 2006 • Science Update
NIMH-funded researchers have discovered how lithium likely fixes body clocks gone awry, stabilizing sleep-wake cycles and other daily rhythms disturbed along with mood in bipolar disorder.
Mice Lacking Social Memory Molecule Take Bullying in Stride
February 9, 2006 • Press Release
The social avoidance that normally develops when a mouse repeatedly experiences defeat by a dominant animal disappears when it lacks a gene for a memory molecule in a brain circuit for social learning, scientists funded by NIMH have discovered.
Stopping Antidepressant Use While Pregnant May Pose Risks
February 1, 2006 • Science Update
Pregnant women who discontinue antidepressant medications may significantly increase their risk of relapse during pregnancy, a new NIMH-funded study has found.
Nobelist Discovers Antidepressant Protein in Mouse Brain
January 6, 2006 • Press Release
A protein that seems to be pivotal in lifting depression has been discovered by a Nobel Laureate researcher funded by NIMH.
Initial Results Help Clinicians Identify Patients with Treatment-Resistant Depression
January 1, 2006 • Press Release
Initial results of the nation’s largest clinical trial for depression have helped clinicians to track “real world” patients who became symptom-free and to identify those who were resistant to the initial treatment.
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