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- Studies Refine Understanding of Treatments for Bipolar Disorder
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September 1, 2007
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Science Update
Two new studies provide additional details on best practices for treating people with bipolar disorder, a sometimes debilitating illness marked by severe mood swings between depression and mania. The two studies are part of the NIMH-funded Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).
- Bipolar Youth Show Distinct Pattern of Brain Development
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August 28, 2007
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Science Update
The first picturess of the brain changing before-and-after the onset of pediatric bipolar disorder reveal a distinct pattern of development, when compared to that seen in healthy youth or in childhood onset schizophrenia.
- Suspect Schizophrenia Genes Act Together to Thwart Working Memory
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August 28, 2007
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Science Update
Two gene variants implicated in schizophrenia interact to degrade the brain's ability to process information, NIMH researchers have discovered. The interaction impaired working memory — retaining information from moment to moment. Such thinking problems are a hallmark of this severe mental illness that affects about one percent of the population.
- Unpleasant Words Trigger Strong Startle Response in People with Borderline Personality Disorder
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August 22, 2007
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Science Update
Adults with borderline personality disorder (BPD) showed excessive emotional reactions when looking at words with unpleasant meanings compared to healthy people during an emotionally stimulating task, according to NIMH-funded researchers. They also found that people with more severe BPD showed a greater difference in emotional responding compared to people with less severe BPD.
- Behavioral Interventions Effective for Preschoolers with ADHD
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August 15, 2007
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Science Update
Two types of early interventions designed to reduce symptoms of attention deficit-hyperactivity disorder (ADHD) in preschoolers may be effective alternatives or additions to medication treatment, according to a recent NIMH-funded study.
- Half of Children With Autism May be Diagnosable Soon After Their First Birthday
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August 10, 2007
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Science Update
About half of children with autism spectrum disorders (ASD) can be diagnosed soon after their first birthday; others with the disorder may appear to develop normally until that age and then falter or regress during their second year, NIMH-funded researchers have discovered.
- Parents' Diagnoses Help to Distinguish Childhood Bipolar Disorder from Severe Mood Dysregulation
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August 6, 2007
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Science Update
The parents of children who have bipolar disorder are more likely to have bipolar disorder themselves than the parents of children who have severe mood dysregulation (SMD). This finding challenges the notion of some research that suggests SMD is a type of more broadly defined childhood bipolar disorder.
- Success or Failure of Antidepressant Citalopram Predicted by Gene Variation
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August 1, 2007
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Press Release
A variation in a gene called GRIK4 appears to make people with depression more likely to respond to the medication citalopram (Celexa) than are people without the variation, a study by NIMH has found.
- Faster-Acting Antidepressants Closer to Becoming a Reality
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July 24, 2007
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Press Release
A new study has revealed more about how the medication ketamine, when used experimentally for depression, relieves symptoms of the disorder in hours instead of the weeks or months it takes for current antidepressants to work.
- Improvement Following ADHD Treatment Sustained in Most Children
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July 20, 2007
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Press Release
Most children treated in a variety of ways for attention deficit hyperactivity disorder (ADHD) showed sustained improvement after three years in a major follow-up study funded by NIMH.
