Intramural Research
Online Research Resources
Autoimmune Lymphoproliferative Syndrome Database (ALPSbase)
|
FAS (TNFRSF6) Polymorphisms
| Exon / Intron | cDNA | AA change | freq Caucasian | freq Af Am |
Reference |
|---|---|---|---|---|---|
| Exon 2 | 240 G or A | Ala or Thr (-1) | G(.99) A(.01) | G(.87) A(.13) | Jackson et al. 1999 |
| Exon 3 | 416 A or G | none | A(.93) G(.07) | A(.99) G(.01) | Fiucci & Ruberti, 1994, C. Jackson, unpublished |
| Exon 4 | 559 C or T | Thr or Ile (106) | C(1.00) | C(.98) T(.02) | Jackson et al. 1999 |
| Intron 5 | 699(+83) g or c | none | G(.42) C(.58) | G(.33) C(.67) | C. Jackson, unpublished |
| Exon 7 | 836 C or T | none | C(.63) T(.37) | C(.66) T(.34) | Fiucci & Ruberti, 1994, C. Jackson, unpublished |
Comments, suggestions and problems to bioinformatics@nhgri.nih.gov
