GeneConnect is a caBIGTM mapping service that makes this interoperability possible by interlinking approved genomic identifiers. These include: Ensembl Gene ID; Ensembl Transcript ID; Ensembl Protein ID; Entrez Gene ID; UniGene ID; GenBank mRNA Accession Number; GenBank Protein Accession Number; RefSeq mRNA Accession Number; RefSeq Protein Accession Number; and UniProtKB Primary Accession Number.

To interlink all of these identifiers, database annotations (either direct or inferred) and an alignment engine have been used to construct pair wise connections, and then all-to-all relationships have been calculated by traversing all possible combinations of edges in the graph using every node as the starting point. For each query, composed of one or more input identifiers and a set of paths that may be traversed, the Path Score and Frequency are calculated. The GeneConnect application is a independent component with following modules GeneConnect server; Web application; XML-RPC server