Spectrin, beta, non-erythrocytic 1, Homo sapiens

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
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Highly represented in many libraries

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

brain; intestine; lung; mixed; mouth; uncharacterized tissue; lymph node; placenta; skin; embryonic tissue; eye; liver; uterus; thyroid; pancreas; mammary gland; testis; heart; blood; stomach; kidney; adipose tissue; prostate; ear; trachea; ganglia; connective tissue; parathyroid; thymus; muscle; bone marrow; ovary; pharynx; vascular; spleen; amniotic fluid; pituitary gland; bladder; ascites; nerve; bone; cervix; larynx; adrenal gland; esophagus; spinal cord; epididymis

NCBI

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Finding cDNAs

UGID:718337 UniGene Hs.503178 Homo sapiens (human) SPTBN1

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Spectrin, beta, non-erythrocytic 1 (SPTBN1)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
XP_865214.1	PREDICTED: similar to Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain) isoform 6	C. lupus familiaris	99.6	2015
XP_001713670.1	PREDICTED: hypothetical protein	H. sapiens	84.1	68
NP_001024052.1	UNCoordinated family member (unc-70)	C. elegans	63.7	2237
NP_958792.1	plectin 1 isoform 7	M. musculus	58.6	227
XP_957320.1	hypothetical protein NCU06429	N. crassa	49.2	191

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	2
	Map position:	2p21

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

AJ005694.1	Homo sapiens mRNA for short form of beta II spectrin, partial
NM_178313.2	Homo sapiens spectrin, beta, non-erythrocytic 1 (SPTBN1), transcript variant 2, mRNA	A
AL117605.1	Homo sapiens mRNA; cDNA DKFZp564N1063 (from clone DKFZp564N1063)
NM_003128.2	Homo sapiens spectrin, beta, non-erythrocytic 1 (SPTBN1), transcript variant 1, mRNA
AB209748.1	Homo sapiens mRNA for spectrin, beta, non-erythrocytic 1 isoform 1 variant protein	P
AK025071.1	Homo sapiens cDNA: FLJ21418 fis, clone COL04072	A
AF218848.1	Homo sapiens beta II spectrin-short isoform mRNA, partial cds
BC137282.1	Homo sapiens spectrin, beta, non-erythrocytic 1, mRNA (cDNA clone MGC:168902 IMAGE:9021279), complete cds	A
BC137283.1	Homo sapiens spectrin, beta, non-erythrocytic 1, mRNA (cDNA clone MGC:168903 IMAGE:9021280), complete cds	A
AB371586.1	Homo sapiens SPTBN1 mRNA for spectrin beta non-erythrocytic 1, complete cds, clone: HP07744-ARiS088A21
AK295570.1	Homo sapiens cDNA FLJ55845 complete cds, highly similar to Spectrin beta chain, brain 1
BC032061.1	Homo sapiens spectrin, beta, non-erythrocytic 1, mRNA (cDNA clone IMAGE:5173539)	P
S65762.1	SPTBN1=beta-fodrin [human, mRNA, 3756 nt]	P
AF327441.1	Homo sapiens beta-spectrin 2 isoform 2 mRNA, complete cds	P

EST sequences (10 of 1398) [Show all sequences]

AA922313.1	Clone IMAGE:1474273	intestine	3' read	A
AA984493.1	Clone IMAGE:1630110	brain	3' read	P
AA984622.1	Clone IMAGE:1629855	brain	3' read	P
AA985089.1	Clone IMAGE:1616190	brain	3' read	P
AA985586.1	Clone IMAGE:1601217	lung	3' read	A
AA911176.1	Clone IMAGE:1520329	kidney	3' read	A
AI002045.1	Clone IMAGE:1637820	mammary gland	3' read	A
AI002805.1	Clone IMAGE:1683802	brain	3' read	P
AI005567.1	Clone IMAGE:1641511	testis	3' read	A
AI014328.1	Clone IMAGE:1539086	brain	3' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria