Collagen, type I, alpha 2, Homo sapiens

Expression Profile:

View expression levels using UniGene's EST ProfileViewer
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Highly represented in many libraries

GEO profiles:

Gene expression profiles in the NCBI Gene Expression Omnibus database

cDNA Sources:

embryonic tissue; bone; ear; eye; uncharacterized tissue; connective tissue; pancreas; lung; skin; bone marrow; uterus; brain; intestine; mixed; placenta; testis; stomach; mammary gland; heart; kidney; nerve; muscle; thyroid; larynx; ovary; amniotic fluid; adipose tissue; prostate; mouth; epididymis; bladder; vascular; spleen; liver; ganglia; pituitary gland; blood; pharynx; esophagus; umbilical cord; adrenal gland; lymph node; pineal gland

NCBI

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Finding cDNAs

UGID:704301 UniGene Hs.489142 Homo sapiens (human) COL1A2

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Collagen, type I, alpha 2 (COL1A2)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
XP_001082513.1	PREDICTED: LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)	M. mulatta	92.7	55
XP_912463.1	PREDICTED: similar to collagen, type XXII, alpha 1, isoform 3	M. musculus	48.6	1182
NP_647970.1	CG10625 CG10625-PA, isoform A	D. melanogaster	48.3	178

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	7
	Map position:	7q22.1

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

BC054498.1	Homo sapiens collagen, type I, alpha 2, mRNA (cDNA clone MGC:57503 IMAGE:6474549), complete cds	PA
NM_000089.3	Homo sapiens collagen, type I, alpha 2 (COL1A2), mRNA	P
J03464.1	Homo sapiens pre-pro-alpha-2 type I collagen (COL1A2) mRNA, complete cds	P
BC042586.1	Homo sapiens collagen, type I, alpha 2, mRNA (cDNA clone MGC:30044 IMAGE:4803351), complete cds	PA
AK223175.1	Homo sapiens mRNA, alpha 2 type I collagen variant, clone: PNC00393	PA
AK226074.1	Homo sapiens mRNA for alpha 2 type I collagen variant, clone: sj01762
Z74616.1	H.sapiens mRNA for prepro-alpha2(I) collagen	P
AK309504.1	Homo sapiens cDNA, FLJ99545
AK300194.1	Homo sapiens cDNA FLJ60884 complete cds, highly similar to Collagen alpha-2(I) chain precursor	A
AK297786.1	Homo sapiens cDNA FLJ56576 complete cds, highly similar to Collagen alpha-2(I) chain precursor
S96821.1	COL1A2=type I procollagen {exons 32, 33 and 41} [human, fibroblasts, mRNA Partial Mutant, 162 nt]
Y00724.1	Human mRNA for prepro-alpha2(I) collagen (COL1A2)	P
X55525.1	H.sapiens mRNA for type I collagen	P
J00114.1	Human collagen type1; pro-alpha-2 chain mrna
V00503.1	Human mRNA encoding Pro-alpha-2 chain of type I procollagen. (major part)	P
L47668.1	Homo sapiens alpha-2 collagen type I (COL1A2) mRNA, with a Gly586Val mutation, causing type III osteogenesis imperfecta

EST sequences (10 of 2860) [Show all sequences]

AA954943.1	Clone IMAGE:1574435	kidney	3' read
AA836845.1	Clone IMAGE:1422677	kidney		P
AA864259.1	Clone IMAGE:1460201	kidney	3' read	P
AA961771.1	Clone IMAGE:1600271	uncharacterized tissue	3' read	PA
AA961949.1	Clone IMAGE:1593779	kidney	3' read
AA969701.1	Clone IMAGE:1574735	kidney	3' read	A
AA970206.1	Clone IMAGE:1575161	kidney	3' read	P
AA970852.1	Clone IMAGE:1572632	kidney	3' read	PA
AA971881.1	Clone IMAGE:1584793	lung	3' read	A
AA983202.1	Clone IMAGE:1590701	kidney	3' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria